Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   H020_RS0110620 Genome accession   NZ_AKVY01000001
Coordinates   1993176..1993883 (+) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1988176..1998883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H020_RS0110600 argR 1989476..1989922 (-) 447 WP_001231472.1 arginine repressor -
  H020_RS0110605 argS 1990058..1991749 (+) 1692 WP_001092737.1 arginine--tRNA ligase -
  H020_RS0110610 - 1992064..1992621 (-) 558 Protein_1970 transposase -
  H020_RS0110615 - 1992607..1993092 (+) 486 WP_001815029.1 cupin domain-containing protein -
  H020_RS0110620 vicR 1993176..1993883 (+) 708 WP_000166475.1 response regulator transcription factor Regulator
  H020_RS0110625 pnpS 1993884..1995215 (+) 1332 WP_000833270.1 two-component system histidine kinase PnpS -
  H020_RS0110630 - 1995382..1996257 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  H020_RS0110635 pstC 1996375..1997238 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  H020_RS0110640 pstA 1997231..1998046 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  H020_RS0110645 pstB 1998048..1998800 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=64969 H020_RS0110620 WP_000166475.1 1993176..1993883(+) (vicR) [Streptococcus pneumoniae TIGR4]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=64969 H020_RS0110620 WP_000166475.1 1993176..1993883(+) (vicR) [Streptococcus pneumoniae TIGR4]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTGACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396

Multiple sequence alignment