Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   L1A19_RS08105 Genome accession   NZ_CP090888
Coordinates   1613070..1613729 (+) Length   219 a.a.
NCBI ID   WP_054383756.1    Uniprot ID   A0A6G2DAH4
Organism   Streptococcus pneumoniae strain PT8465     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1608070..1618729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A19_RS08080 (L1A19_08080) - 1608375..1608692 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  L1A19_RS08085 (L1A19_08085) - 1608707..1609603 (-) 897 WP_000825665.1 PEP phosphonomutase -
  L1A19_RS08090 (L1A19_08090) - 1609606..1610868 (-) 1263 WP_000413345.1 PTS sugar transporter subunit IIC -
  L1A19_RS08095 (L1A19_08095) - 1611148..1612326 (+) 1179 WP_049479675.1 ROK family transcriptional regulator -
  L1A19_RS08100 (L1A19_08100) - 1612554..1613000 (-) 447 WP_000155402.1 GNAT family N-acetyltransferase -
  L1A19_RS08105 (L1A19_08105) cclA/cilC 1613070..1613729 (+) 660 WP_054383756.1 A24 family peptidase Machinery gene
  L1A19_RS08110 (L1A19_08110) - 1613781..1614932 (-) 1152 WP_024477883.1 XRE family transcriptional regulator -
  L1A19_RS08115 (L1A19_08115) - 1614947..1615678 (-) 732 WP_000934016.1 hypothetical protein -
  L1A19_RS08120 (L1A19_08120) - 1615907..1616008 (+) 102 Protein_1626 prepilin peptidase -
  L1A19_RS08125 (L1A19_08125) trpA 1615980..1616756 (-) 777 WP_001127011.1 tryptophan synthase subunit alpha -
  L1A19_RS08130 (L1A19_08130) trpB 1616749..1617972 (-) 1224 WP_000331293.1 tryptophan synthase subunit beta -
  L1A19_RS08135 (L1A19_08135) - 1617950..1618549 (-) 600 WP_000169895.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24837.91 Da        Isoelectric Point: 7.6418

>NTDB_id=646060 L1A19_RS08105 WP_054383756.1 1613070..1613729(+) (cclA/cilC) [Streptococcus pneumoniae strain PT8465]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=646060 L1A19_RS08105 WP_054383756.1 1613070..1613729(+) (cclA/cilC) [Streptococcus pneumoniae strain PT8465]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G2DAH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

93.151

100

0.932
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868