Detailed information NTG0645972

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: L1A18_RS04265
• Genome accession: NZ_CP090887
• Coordinates: 851571..852524 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain NP7536
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 846571..857524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A18_RS04240 (L1A18_04240)	rpmG	847314..847463 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
L1A18_RS04245 (L1A18_04245)	secG	847503..847736 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
L1A18_RS04250 (L1A18_04250)	rnr	847838..850192 (+)	2355	WP_000654920.1	ribonuclease R	-
L1A18_RS04255 (L1A18_04255)	smpB	850155..850622 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
L1A18_RS04260 (L1A18_04260)	tehB	850638..851498 (+)	861	WP_000413769.1	SAM-dependent methyltransferase TehB	-
L1A18_RS04265 (L1A18_04265)	coiA	851571..852524 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
L1A18_RS04270 (L1A18_04270)	pepF	852543..854345 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
L1A18_RS04275 (L1A18_04275)	-	854347..855060 (+)	714	WP_000230399.1	O-methyltransferase	-
L1A18_RS04280 (L1A18_04280)	prsA	855127..856068 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
L1A18_RS04285 (L1A18_04285)	-	856187..856528 (-)	342	Protein_852	IS3 family transposase	-
L1A18_RS04290 (L1A18_04290)	-	856941..857036 (+)	96	Protein_853	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=645972 L1A18_RS04265 WP_000495909.1 851571..852524(+) (coiA) [Streptococcus pneumoniae strain NP7536]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=645972 L1A18_RS04265 WP_000495909.1 851571..852524(+) (coiA) [Streptococcus pneumoniae strain NP7536]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435