Detailed information NTG0645945

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: L1A17_RS09215
• Genome accession: NZ_CP090886
• Coordinates: 1783130..1785370 (-)
• Length: 746 a.a.
• NCBI ID: WP_238873862.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP7513
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1778130..1790370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A17_RS09180 (L1A17_09180)	-	1779040..1779420 (-)	381	WP_000157154.1	VOC family protein	-
L1A17_RS09185 (L1A17_09185)	rplT	1779478..1779837 (-)	360	WP_000124836.1	50S ribosomal protein L20	-
L1A17_RS09190 (L1A17_09190)	rpmI	1779889..1780089 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
L1A17_RS09195 (L1A17_09195)	infC	1780122..1780652 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
L1A17_RS09200 (L1A17_09200)	-	1780959..1782140 (-)	1182	WP_000655956.1	hypothetical protein	-
L1A17_RS09205 (L1A17_09205)	-	1782144..1782731 (-)	588	WP_000933542.1	ABC transporter ATP-binding protein	-
L1A17_RS09210 (L1A17_09210)	-	1782763..1782951 (-)	189	WP_001809102.1	hypothetical protein	-
L1A17_RS09215 (L1A17_09215)	comEC/celB	1783130..1785370 (-)	2241	WP_238873862.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
L1A17_RS09220 (L1A17_09220)	comEA/celA/cilE	1785354..1786004 (-)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
L1A17_RS09225 (L1A17_09225)	-	1786072..1786641 (-)	570	WP_126418320.1	GNAT family N-acetyltransferase	-
L1A17_RS09230 (L1A17_09230)	ald	1786818..1787929 (+)	1112	Protein_1786	alanine dehydrogenase	-
L1A17_RS09235 (L1A17_09235)	-	1788230..1788556 (-)	327	Protein_1787	TfoX/Sxy family protein	-
L1A17_RS09240 (L1A17_09240)	-	1788559..1789059 (-)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
L1A17_RS09245 (L1A17_09245)	-	1789252..1790220 (-)	969	WP_000658183.1	PhoH family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84630.14 Da
• Isoelectric Point: 9.3408

>NTDB_id=645945 L1A17_RS09215 WP_238873862.1 1783130..1785370(-) (comEC/celB) [Streptococcus pneumoniae strain NP7513]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNSDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVVKIDQLILTNTDK
EHVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPREIGYGGHEDSLVLYGKL
LNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=645945 L1A17_RS09215 WP_238873862.1 1783130..1785370(-) (comEC/celB) [Streptococcus pneumoniae strain NP7513]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATAGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCAATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGTTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGGTGACTAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGTGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGTACTTGCCCATTTTCG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGGAAATTGGATATGGAGGTCATGAAGATTCCCTGGTTCTTTATGGGAAACTC
TTGAATAATCACTTTCTCTTCATAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGTATTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-632)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	96.113	100	0.961
comEC/celB	Streptococcus pneumoniae D39	96.113	100	0.961
comEC/celB	Streptococcus pneumoniae R6	96.113	100	0.961
comEC/celB	Streptococcus pneumoniae Rx1	96.113	100	0.961
comEC/celB	Streptococcus mitis NCTC 12261	91.409	99.866	0.913
comEC/celB	Streptococcus mitis SK321	91.153	100	0.912
comEC	Lactococcus lactis subsp. cremoris KW2	43.725	99.33	0.434