Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG/cglG   Type   Machinery gene
Locus tag   L1A14_RS00250 Genome accession   NZ_CP090883
Coordinates   39610..40023 (+) Length   137 a.a.
NCBI ID   WP_000265624.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LE4448     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 34610..45023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A14_RS00210 (L1A14_00210) - 34663..35721 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  L1A14_RS00215 (L1A14_00215) - 35872..36237 (+) 366 WP_000286415.1 DUF1033 family protein -
  L1A14_RS00220 (L1A14_00220) comGA/cglA/cilD 36313..37254 (+) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A14_RS00225 (L1A14_00225) comGB/cglB 37202..38218 (+) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A14_RS00230 (L1A14_00230) comGC/cglC 38220..38546 (+) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  L1A14_RS00235 (L1A14_00235) comGD/cglD 38539..38943 (+) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A14_RS00240 (L1A14_00240) comGE/cglE 38906..39208 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  L1A14_RS00245 (L1A14_00245) comGF/cglF 39171..39632 (+) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A14_RS00250 (L1A14_00250) comGG/cglG 39610..40023 (+) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  L1A14_RS00255 (L1A14_00255) - 40160..40754 (+) 595 Protein_35 methyltransferase domain-containing protein -
  L1A14_RS00260 (L1A14_00260) comYH 40815..41768 (+) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  L1A14_RS00265 (L1A14_00265) - 41819..43009 (+) 1191 WP_000167765.1 acetate kinase -
  L1A14_RS10350 - 43010..43141 (+) 132 WP_000768904.1 hypothetical protein -
  L1A14_RS00270 (L1A14_00270) rnpA 43158..43529 (+) 372 WP_000739244.1 ribonuclease P protein component -
  L1A14_RS00275 (L1A14_00275) - 43504..44328 (+) 825 WP_001809383.1 membrane protein insertase YidC -

Sequence


Protein


Download         Length: 137 a.a.        Molecular weight: 15955.42 Da        Isoelectric Point: 10.2472

>NTDB_id=645658 L1A14_RS00250 WP_000265624.1 39610..40023(+) (comGG/cglG) [Streptococcus pneumoniae strain LE4448]
MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNKEKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKK
TGLVTRVRTDKSQYEFLFPSVKIKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS

Nucleotide


Download         Length: 414 bp        

>NTDB_id=645658 L1A14_RS00250 WP_000265624.1 39610..40023(+) (comGG/cglG) [Streptococcus pneumoniae strain LE4448]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGTGTTCTCCTCTACGCAGTCACCATAGCAGCCATCTTTAGTCTTTTGTTGCA
ATTTTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTTTGAATAAAGAAAAATTGGTTGCTTTTGCTATGGCTA
AACGAACCAAAGATAAGGTTGAGCAAGAAAGTGGGGAACAGGTTTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTAGTGACGAGGGTTCGTACGGATAAGAGCCAATATGAGTTTCTGTTTCCTTCAGTCAAAATCAAAGAAGAGAA
AAGAGATAAAAAGGAAGAGGTAGCGACCGATTCAAGCGAAAAAGTGGAGAAGAAAAAATCAGAAGAGAAGCCTGAAAAGA
AAGAGAATTCCTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG/cglG Streptococcus pneumoniae Rx1

99.27

100

0.993

  comGG/cglG Streptococcus pneumoniae D39

99.27

100

0.993

  comGG/cglG Streptococcus pneumoniae R6

99.27

100

0.993

  comGG/cglG Streptococcus pneumoniae TIGR4

99.27

100

0.993

  comGG/cglG Streptococcus mitis SK321

87.591

100

0.876

  comGG/cglG Streptococcus mitis NCTC 12261

89.256

88.321

0.788

  comYG Streptococcus mutans UA140

38.806

97.81

0.38

  comYG Streptococcus mutans UA159

38.806

97.81

0.38