Detailed information    

insolico Bioinformatically predicted

Overview

Name   tfoX   Type   Regulator
Locus tag   L0994_RS08970 Genome accession   NZ_CP090847
Coordinates   1995682..1996263 (-) Length   193 a.a.
NCBI ID   WP_016788025.1    Uniprot ID   A0A7Z1S1S6
Organism   Vibrio cyclitrophicus strain WXL032     
Function   master regulator of natural competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 1990682..2001263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L0994_RS08950 (L0994_08920) - 1990728..1991990 (-) 1263 WP_010441447.1 DUF945 family protein -
  L0994_RS08955 (L0994_08925) - 1992174..1994117 (+) 1944 WP_032545401.1 ATP-binding protein -
  L0994_RS08960 (L0994_08930) - 1994110..1994607 (+) 498 WP_010441451.1 response regulator -
  L0994_RS08965 (L0994_08935) - 1995007..1995549 (+) 543 WP_004734692.1 hypothetical protein -
  L0994_RS08970 (L0994_08940) tfoX 1995682..1996263 (-) 582 WP_016788025.1 TfoX/Sxy family DNA transformation protein Regulator
  L0994_RS08975 (L0994_08945) - 1996621..1997541 (+) 921 WP_010441455.1 HDOD domain-containing protein -
  L0994_RS08980 (L0994_08950) - 1997596..1998501 (+) 906 WP_010441460.1 lysine exporter LysO family protein -
  L0994_RS08985 (L0994_08955) - 1998676..1999203 (+) 528 WP_010441462.1 hypothetical protein -
  L0994_RS08990 (L0994_08960) panP 1999323..2000966 (+) 1644 WP_016800901.1 pyridoxal-dependent aspartate 1-decarboxylase PanP -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 22180.69 Da        Isoelectric Point: 9.7662

>NTDB_id=645224 L0994_RS08970 WP_016788025.1 1995682..1996263(-) (tfoX) [Vibrio cyclitrophicus strain WXL032]
MTETAFINYMNQFGKHQKRSMFGGMGLFQNDAMFALLSEGCLFIRGGKSLDKKLADLDCEKYRHVKKQTTATVNYYDITD
LFTCEHPDLDSIIRTSIDNSIQQRSFKKSSASRRLRDLPNMQLTLERMVKKAGVDDVSMFMQLGAPEVFSKVRKAYGNDV
DLKLLWKFAGAIDGIHWKLLQEPRKQQLLKSCH

Nucleotide


Download         Length: 582 bp        

>NTDB_id=645224 L0994_RS08970 WP_016788025.1 1995682..1996263(-) (tfoX) [Vibrio cyclitrophicus strain WXL032]
ATGACCGAGACAGCATTTATTAATTACATGAATCAATTTGGTAAGCATCAAAAACGTTCTATGTTCGGAGGTATGGGCCT
CTTTCAAAATGACGCCATGTTCGCTTTGTTGAGCGAAGGTTGTTTATTTATTAGAGGTGGAAAGTCATTAGATAAAAAAC
TGGCAGATCTTGATTGTGAAAAGTATCGTCATGTAAAAAAACAGACGACAGCAACCGTAAACTATTACGATATTACTGAC
TTGTTTACATGTGAACACCCTGATTTGGATAGCATTATTCGTACTTCAATCGATAATTCAATTCAGCAACGTAGCTTCAA
AAAATCATCAGCTAGCCGTCGATTGAGAGATCTTCCGAACATGCAACTTACACTAGAGCGCATGGTTAAGAAGGCGGGTG
TGGATGATGTTTCAATGTTTATGCAGCTAGGCGCACCTGAAGTGTTTAGTAAGGTTCGCAAAGCGTACGGCAATGATGTT
GACCTAAAACTACTTTGGAAATTTGCGGGTGCAATTGATGGTATCCATTGGAAACTGTTACAAGAACCACGCAAGCAGCA
ATTATTAAAGAGCTGCCACTAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(9-98)

TfoX C-terminal domain (TfoX_C)

(112-190)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Z1S1S6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  tfoX Vibrio cholerae O1 biovar El Tor str. N16961

72.021

100

0.72
  tfoX Vibrio cholerae O1 biovar El Tor strain DRC-193A

72.021

100

0.72
  tfoX Vibrio cholerae O1 biovar El Tor strain P27459

72.021

100

0.72
  tfoX Vibrio cholerae O1 biovar El Tor strain E7946

72.021

100

0.72
  tfoX Vibrio cholerae strain A1552

72.021

100

0.72
  tfoX Vibrio campbellii strain DS40M4

67.876

100

0.679
  tfoX Vibrio parahaemolyticus RIMD 2210633

67.876

100

0.679
  tfoX Aliivibrio fischeri ES114

57.368

98.446

0.565