Detailed information NTG0643178

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: LOD78_RS03305
• Genome accession: NZ_CP090522
• Coordinates: 640279..642516 (+)
• Length: 745 a.a.
• NCBI ID: WP_274505722.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SS17
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 635279..647516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LOD78_RS03275 (LOD78_03260)	-	636549..636956 (+)	408	WP_239604637.1	GNAT family N-acetyltransferase	-
LOD78_RS03280 (LOD78_03265)	-	637077..637688 (+)	612	WP_171988541.1	NAD(P)H-dependent oxidoreductase	-
LOD78_RS03285 (LOD78_03270)	-	637706..637978 (-)	273	WP_239604638.1	GIY-YIG nuclease family protein	-
LOD78_RS03290 (LOD78_03275)	-	637968..638717 (-)	750	WP_239604639.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
LOD78_RS03295 (LOD78_03280)	-	638809..639552 (+)	744	WP_172036418.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
LOD78_RS03300 (LOD78_03285)	-	639618..640295 (+)	678	WP_274505721.1	helix-hairpin-helix domain-containing protein	-
LOD78_RS03305 (LOD78_03290)	comEC/celB	640279..642516 (+)	2238	WP_274505722.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LOD78_RS03310 (LOD78_03295)	holA	642580..643611 (+)	1032	WP_274505723.1	DNA polymerase III subunit delta	-
LOD78_RS03315 (LOD78_03300)	sodA	643688..644293 (+)	606	WP_171988548.1	superoxide dismutase SodA	-
LOD78_RS03320 (LOD78_03305)	rplS	644495..644842 (+)	348	WP_011921928.1	50S ribosomal protein L19	-
LOD78_RS03325 (LOD78_03310)	-	645115..646854 (+)	1740	WP_171988549.1	ABC transporter transmembrane domain-containing protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84307.44 Da
• Isoelectric Point: 6.9651

>NTDB_id=643178 LOD78_RS03305 WP_274505722.1 640279..642516(+) (comEC/celB) [Streptococcus parasuis strain SS17]
MSRLIRLPCQPIHFAVLAVLAYFAVHSFSLLTMSLLSLLLAVFGLRQGKEVFIKTLPLLALCGLFFGCQKIQWERTNQWA
PEQVTTVQVIPDTIDVNGDSLSFRGRTEGQVFQVFYKLASQEEQTYFQELTDLVQLEVDAEVSQPAGQRNFNGFDYQAYL
KTQGIYRTVKISTINKIFPIHSWNIFDWLSTWRRQALVYIKSHFPAPMSHYMTGLLLGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWLLLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAATVFVCLLLM
PRFLLTAGGVLTFTYALLLTVFDFEELRQLKKVAVESLSISLGILPVLMSYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
ILLLSPFIKITWVNGFFILMEKIIVWVAELGISPWILGKPTGLVFLLLLVCLFLLYDFHREKKCLLGLSLMLALLFFITK
HPLENEVTVVDVGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWRERSREANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HAGDVLEVAKQIQIGKIYVSPGSLTVPDFVATLRKINVPVHVVNPGDRLPIFDSYLEVLYPNRIGDGGNNDSIVLYGRLL
KMNFLFTGDLEQGELDLITSYPQLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGENNRYQHPHQETLERFDSQNMQ
VYRTDLQGAIRFRGWKQWSIETVKE

Nucleotide

• Length: 2238 bp

>NTDB_id=643178 LOD78_RS03305 WP_274505722.1 640279..642516(+) (comEC/celB) [Streptococcus parasuis strain SS17]
ATGTCACGGTTGATTAGACTCCCCTGTCAGCCCATTCACTTTGCAGTTTTGGCGGTGTTAGCCTACTTTGCTGTTCACTC
TTTTTCCCTTTTGACAATGAGCCTGCTGAGTCTGTTACTAGCAGTCTTTGGGCTTCGGCAAGGAAAGGAGGTCTTCATCA
AAACGCTACCGCTTCTAGCCTTATGTGGTCTCTTCTTCGGATGTCAGAAGATACAATGGGAGCGGACAAATCAATGGGCT
CCAGAGCAAGTGACAACTGTGCAGGTTATTCCTGATACCATTGATGTCAACGGAGACAGTCTATCTTTTCGTGGTCGGAC
TGAAGGTCAAGTTTTTCAGGTTTTCTATAAACTTGCAAGTCAGGAAGAACAAACCTATTTTCAGGAGCTTACGGACTTGG
TGCAGTTAGAGGTAGATGCAGAAGTTAGCCAACCAGCAGGTCAACGTAATTTCAATGGTTTTGATTATCAGGCTTATCTC
AAAACCCAGGGCATCTATCGGACAGTAAAAATAAGTACCATTAACAAAATTTTCCCTATTCATTCCTGGAATATCTTTGA
CTGGTTGTCAACCTGGCGGAGGCAGGCTCTCGTTTATATCAAATCTCATTTTCCTGCTCCAATGAGCCACTACATGACTG
GATTACTATTGGGAGAGTTAGATAGTGACTTTGACCAAATGAGTGACCTCTATTCTAGTTTAGGGATCATTCATCTTTTT
GCCCTGTCTGGGATGCAGGTTGGTTTTTTCATTGACAAATTTCGCTGGCTTTTATTGCGTTTGGGTTTAACCAAGGAAAC
TGTCGATAAGCTTCAAATTCCATTTTCTCTTGTTTATGCAGGATTGACAGGATTTTCAGTCTCAGTCGTGCGGTCCTTGG
TCCAGAAAATTCTGGGTAATCTTGGACTACGAAAATTGGATAATTTTGCAGCAACAGTCTTTGTTTGTCTCTTGCTTATG
CCACGGTTTCTTCTGACTGCAGGCGGTGTGCTAACATTTACCTATGCTTTGTTATTGACAGTCTTTGATTTTGAAGAGCT
AAGGCAACTTAAGAAGGTAGCAGTGGAGAGTCTGAGTATTTCTCTTGGAATTTTACCGGTCTTGATGTCCTATTTTTTTG
CCTTTCAGCCCTTATCTATCCTTTTAACGTTTGTTTTTTCCTTTGTTTTTGATGTGTTGTTGTTACCTGGGCTATCTGTC
ATTCTTTTACTATCGCCCTTCATTAAAATTACGTGGGTCAACGGATTCTTTATCCTTATGGAAAAGATTATTGTATGGGT
GGCAGAATTGGGGATTAGCCCTTGGATTTTAGGAAAACCTACGGGCCTTGTCTTTTTGCTCTTGCTGGTCTGCCTTTTCT
TGCTTTATGATTTTCACAGAGAGAAGAAATGCCTCCTAGGACTGAGCCTGATGCTTGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTAGACGTAGGGCAGGGGGATAGTATCTTTTTGCGGGACATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGTGGTCGGGTTGACTTTGCTGCAAAGGAAGCTTGGCGGGAGCGGTCTAGGGAAGCAAATGCGG
AGCGAACTCTGATTCCTTACCTGCATAGTCGAGGTGTGGATAGGATTGATAGCTTAGTCTTGACCCATACCGATGCAGAT
CATGCGGGTGATGTGCTAGAAGTGGCTAAGCAGATTCAGATCGGTAAGATTTACGTTTCTCCAGGTAGTTTGACTGTACC
AGATTTTGTTGCGACTTTGAGGAAAATAAATGTCCCTGTTCATGTTGTAAATCCTGGAGATCGATTGCCCATTTTTGATT
CCTATCTAGAAGTTCTATACCCCAATAGAATCGGAGATGGAGGCAATAATGACTCAATTGTACTCTATGGTCGTTTGTTA
AAAATGAATTTCCTCTTTACCGGTGACTTGGAGCAAGGGGAATTAGATTTAATCACTTCTTATCCGCAGCTACCAGTCGA
TGTGCTGAAAGCAGGTCACCATGGCTCCAAGGGCTCTTCATATCCAGAATTTTTAGACCATATTGGAGCAAAAATTGCTC
TGATTTCTGCAGGTGAAAATAATCGCTATCAACATCCGCATCAGGAAACTCTGGAACGTTTCGACAGTCAAAATATGCAG
GTTTACCGAACGGATCTGCAAGGAGCAATCCGTTTCCGAGGTTGGAAACAGTGGAGTATTGAAACGGTAAAAGAGTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.315	99.195	0.529
comEC/celB	Streptococcus mitis NCTC 12261	52.861	98.523	0.521
comEC/celB	Streptococcus pneumoniae TIGR4	52.109	98.658	0.514
comEC/celB	Streptococcus pneumoniae Rx1	51.429	98.658	0.507
comEC/celB	Streptococcus pneumoniae D39	51.429	98.658	0.507
comEC/celB	Streptococcus pneumoniae R6	51.429	98.658	0.507
comEC	Lactococcus lactis subsp. cremoris KW2	47.797	100	0.481