Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   LV497_RS00940 Genome accession   NZ_CP090007
Coordinates   204761..206176 (-) Length   471 a.a.
NCBI ID   WP_084869337.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 199761..211176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS00910 (LV497_00910) - 200399..200797 (-) 399 WP_021144038.1 cytidine deaminase -
  LV497_RS00915 (LV497_00915) deoC 200802..201446 (-) 645 WP_014634599.1 deoxyribose-phosphate aldolase -
  LV497_RS00920 (LV497_00920) - 201480..202757 (-) 1278 WP_104021054.1 pyrimidine-nucleoside phosphorylase -
  LV497_RS00925 (LV497_00925) - 202754..203344 (-) 591 WP_045768632.1 class I SAM-dependent methyltransferase -
  LV497_RS00930 (LV497_00930) coaA 203457..204377 (+) 921 WP_104021193.1 type I pantothenate kinase -
  LV497_RS00935 (LV497_00935) rpsT 204447..204683 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  LV497_RS00940 (LV497_00940) ciaH 204761..206176 (-) 1416 WP_084869337.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LV497_RS00945 (LV497_00945) ciaR 206166..206840 (-) 675 WP_073688405.1 response regulator transcription factor Regulator
  LV497_RS00950 (LV497_00950) - 207037..208707 (-) 1671 WP_245084905.1 formate--tetrahydrofolate ligase -
  LV497_RS00955 (LV497_00955) - 208902..209585 (+) 684 WP_084869336.1 phosphopantothenate--cysteine ligase -
  LV497_RS00960 (LV497_00960) coaC 209578..210123 (+) 546 WP_084869334.1 phosphopantothenoylcysteine decarboxylase -
  LV497_RS00965 (LV497_00965) - 210152..210724 (+) 573 WP_245084908.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53480.22 Da        Isoelectric Point: 8.7661

>NTDB_id=640092 LV497_RS00940 WP_084869337.1 204761..206176(-) (ciaH) [Streptococcus salivarius strain SALI-10]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGATTETSDSSDSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTSQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVIALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=640092 LV497_RS00940 WP_084869337.1 204761..206176(-) (ciaH) [Streptococcus salivarius strain SALI-10]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACGACCATTTACCAGGCTTATGATACTAAAGGGGCGACAACTGAAACATCTGACTCGAGTGA
CTCTAAGAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCTGTTGCGGCAAATACTAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTATCGTCTGATCACTGAGAAAGT
AGACAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAGGTTCTTTTCCGTAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTTCGTAATATGCGTCTTTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGTCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTCCGCACTAACGATCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAGAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTATAGCCCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAAATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae D39

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae R6

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae TIGR4

50.431

98.514

0.497