Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   LXA46_RS10685 Genome accession   NZ_CP089948
Coordinates   2120556..2121218 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae TIGR4     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2115556..2126218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS10660 (LXA46_10645) - 2115706..2115972 (-) 267 WP_001278167.1 Veg family protein -
  LXA46_RS10665 (LXA46_10650) dnaB 2115974..2117326 (-) 1353 WP_000852486.1 replicative DNA helicase -
  LXA46_RS10670 (LXA46_10655) rplI 2117370..2117822 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  LXA46_RS10675 (LXA46_10660) - 2117819..2119792 (-) 1974 WP_000715115.1 DHH family phosphoesterase -
  LXA46_RS10680 (LXA46_10665) raiA 2119928..2120476 (-) 549 WP_000599104.1 ribosome-associated translation inhibitor RaiA -
  LXA46_RS10685 (LXA46_10670) comFC/cflB 2120556..2121218 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  LXA46_RS10690 (LXA46_10675) comFA/cflA 2121215..2122513 (-) 1299 WP_000867616.1 DEAD/DEAH box helicase Machinery gene
  LXA46_RS10695 (LXA46_10680) - 2122569..2123204 (+) 636 WP_000395742.1 YigZ family protein -
  LXA46_RS10700 (LXA46_10685) cysK 2123453..2124373 (+) 921 WP_000029866.1 cysteine synthase A -
  LXA46_RS10705 (LXA46_10690) - 2124612..2124977 (-) 366 Protein_2103 IS66 family transposase -
  LXA46_RS10710 (LXA46_10695) - 2124959..2125246 (+) 288 Protein_2104 transposase -
  LXA46_RS10715 (LXA46_10700) tnpB 2125387..2125710 (-) 324 WP_000586642.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=639375 LXA46_RS10685 WP_000649971.1 2120556..2121218(-) (comFC/cflB) [Streptococcus pneumoniae TIGR4]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=639375 LXA46_RS10685 WP_000649971.1 2120556..2121218(-) (comFC/cflB) [Streptococcus pneumoniae TIGR4]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914