Detailed information NTG0639326

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: LXA46_RS04575
• Genome accession: NZ_CP089948
• Coordinates: 923820..924773 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae TIGR4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 918820..929773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXA46_RS04550 (LXA46_04540)	rpmG	919563..919712 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
LXA46_RS04555 (LXA46_04545)	secG	919752..919985 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
LXA46_RS04560 (LXA46_04550)	rnr	920087..922441 (+)	2355	WP_000654907.1	ribonuclease R	-
LXA46_RS04565 (LXA46_04555)	smpB	922404..922871 (+)	468	WP_001051747.1	SsrA-binding protein SmpB	-
LXA46_RS04570 (LXA46_04560)	tehB	922887..923747 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
LXA46_RS04575 (LXA46_04565)	coiA	923820..924773 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
LXA46_RS04580 (LXA46_04570)	pepF	924792..926594 (+)	1803	WP_000244116.1	oligoendopeptidase F	Regulator
LXA46_RS04585 (LXA46_04575)	-	926596..927309 (+)	714	WP_000230399.1	O-methyltransferase	-
LXA46_RS04590 (LXA46_04580)	prsA	927376..928317 (+)	942	WP_000727952.1	peptidylprolyl isomerase PrsA	-
LXA46_RS04595 (LXA46_04585)	-	928435..928776 (-)	342	Protein_922	IS3 family transposase	-
LXA46_RS04600 (LXA46_04590)	-	929189..929284 (+)	96	Protein_923	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=639326 LXA46_RS04575 WP_000495909.1 923820..924773(+) (coiA) [Streptococcus pneumoniae TIGR4]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=639326 LXA46_RS04575 WP_000495909.1 923820..924773(+) (coiA) [Streptococcus pneumoniae TIGR4]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435