Detailed information NTG0635334

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: LRO88_RS19985
• Genome accession: NZ_CP089148
• Coordinates: 3666926..3668083 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain NIB353
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3661926..3673083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LRO88_RS19955	yvyF	3662179..3662598 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
LRO88_RS19960	comFC	3662672..3663394 (-)	723	WP_124047882.1	comF operon protein ComFC	Machinery gene
LRO88_RS19965	comFB	3663358..3663654 (-)	297	WP_015483764.1	late competence protein ComFB	-
LRO88_RS19970	comFA	3663714..3665105 (-)	1392	WP_072173458.1	ATP-dependent helicase ComFA	Machinery gene
LRO88_RS19975	fakBA	3665211..3666056 (-)	846	WP_014481053.1	DegV family protein	-
LRO88_RS19980	degU	3666154..3666843 (-)	690	WP_014481054.1	two-component system response regulator DegU	Regulator
LRO88_RS19985	degS	3666926..3668083 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
LRO88_RS19990	yvyE	3668300..3668953 (+)	654	WP_003227979.1	YigZ family protein	-
LRO88_RS19995	tagV	3668953..3670128 (+)	1176	WP_072173456.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
LRO88_RS20000	tagO	3670201..3671277 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
LRO88_RS20005	tuaH	3671422..3672615 (-)	1194	WP_153257382.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=635334 LRO88_RS19985 WP_003227983.1 3666926..3668083(-) (degS) [Bacillus subtilis strain NIB353]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=635334 LRO88_RS19985 WP_003227983.1 3666926..3668083(-) (degS) [Bacillus subtilis strain NIB353]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGGATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1