Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   CSB63_RS01650 Genome accession   NZ_CP089060
Coordinates   295035..296552 (+) Length   505 a.a.
NCBI ID   WP_002949640.1    Uniprot ID   A0A060BQ50
Organism   Streptococcus thermophilus strain CH8     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 290035..301552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSB63_RS01620 - 290315..290485 (+) 171 Protein_269 ascorbate 6-phosphate lactonase -
  CSB63_RS01625 (CSB63_0297) - 290502..291173 (-) 672 WP_002946492.1 potassium channel family protein -
  CSB63_RS01630 (CSB63_0298) - 291213..292577 (-) 1365 WP_134973078.1 TrkH family potassium uptake protein -
  CSB63_RS01635 (CSB63_0299) rsmG 292647..293360 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  CSB63_RS01640 (CSB63_0300) - 293657..294193 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  CSB63_RS01645 (CSB63_0301) covR 294349..295038 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  CSB63_RS01650 (CSB63_0302) covS 295035..296552 (+) 1518 WP_002949640.1 HAMP domain-containing sensor histidine kinase Regulator
  CSB63_RS01655 (CSB63_0303) nrdR 296675..297154 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  CSB63_RS01660 (CSB63_0304) - 297151..298326 (+) 1176 WP_100262514.1 DnaD domain protein -
  CSB63_RS01665 (CSB63_0305) dnaI 298330..299232 (+) 903 WP_084828487.1 primosomal protein DnaI -
  CSB63_RS01670 (CSB63_0306) der 299338..300648 (+) 1311 WP_084828488.1 ribosome biogenesis GTPase Der -
  CSB63_RS01675 - 300712..301380 (+) 669 Protein_280 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57536.93 Da        Isoelectric Point: 5.2689

>NTDB_id=634854 CSB63_RS01650 WP_002949640.1 295035..296552(+) (covS) [Streptococcus thermophilus strain CH8]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=634854 CSB63_RS01650 WP_002949640.1 295035..296552(+) (covS) [Streptococcus thermophilus strain CH8]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BQ50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.622

99.406

0.941