Detailed information NTG0634849

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CSB63_RS01460
• Genome accession: NZ_CP089060
• Coordinates: 261007..261906 (+)
• Length: 299 a.a.
• NCBI ID: WP_100262298.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CH8
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 256007..266906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB63_RS01440 (CSB63_0258)	trkA	257144..258493 (-)	1350	WP_024704181.1	Trk system potassium transporter TrkA	-
CSB63_RS01445 (CSB63_0259)	-	258752..259291 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
CSB63_RS01450 (CSB63_0260)	-	259602..260159 (+)	558	WP_111679227.1	ECF transporter S component	-
CSB63_RS01455 (CSB63_0261)	-	260162..260812 (+)	651	WP_134973069.1	phosphatase PAP2 family protein	-
CSB63_RS01460 (CSB63_0262)	comR	261007..261906 (+)	900	WP_100262298.1	helix-turn-helix domain-containing protein	Regulator
CSB63_RS01465	-	262144..262440 (+)	297	Protein_238	cysteine peptidase family C39 domain-containing protein	-
CSB63_RS01470	comA	262606..263001 (+)	396	WP_252989162.1	ABC transporter transmembrane domain-containing protein	Regulator
CSB63_RS01475 (CSB63_0265)	comA	263085..263453 (+)	369	WP_255136094.1	ABC transporter transmembrane domain-containing protein	Regulator
CSB63_RS01480 (CSB63_0266)	-	263538..264713 (+)	1176	WP_159341049.1	IS256-like element IS1191 family transposase	-
CSB63_RS01485 (CSB63_0268)	comA	264931..265500 (+)	570	WP_065972905.1	ATP-binding cassette domain-containing protein	Regulator
CSB63_RS01490 (CSB63_0269)	-	265607..265939 (+)	333	WP_024704184.1	DUF805 domain-containing protein	-
CSB63_RS01495 (CSB63_0270)	-	266085..266564 (-)	480	WP_224107489.1	DUF4153 domain-containing protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35331.82 Da
• Isoelectric Point: 5.1073

>NTDB_id=634849 CSB63_RS01460 WP_100262298.1 261007..261906(+) (comR) [Streptococcus thermophilus strain CH8]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALVVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=634849 CSB63_RS01460 WP_100262298.1 261007..261906(+) (comR) [Streptococcus thermophilus strain CH8]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTGTTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGCAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGTTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421