Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   LPC11_RS07735 Genome accession   NZ_CP088218
Coordinates   1616063..1616932 (-) Length   289 a.a.
NCBI ID   WP_041613962.1    Uniprot ID   A0A2J6P192
Organism   Staphylococcus sp. HL28     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1611063..1621932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPC11_RS07720 (LPC11_07720) xerC 1611326..1612219 (-) 894 WP_041613964.1 tyrosine recombinase XerC -
  LPC11_RS07725 (LPC11_07725) trmFO 1612386..1613693 (-) 1308 WP_023375179.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  LPC11_RS07730 (LPC11_07730) topA 1613810..1615885 (-) 2076 WP_231307395.1 type I DNA topoisomerase -
  LPC11_RS07735 (LPC11_07735) dprA 1616063..1616932 (-) 870 WP_041613962.1 DNA-processing protein DprA Machinery gene
  LPC11_RS07740 (LPC11_07740) sucD 1617173..1618078 (-) 906 WP_002466045.1 succinate--CoA ligase subunit alpha -
  LPC11_RS07745 (LPC11_07745) sucC 1618100..1619266 (-) 1167 WP_023375176.1 ADP-forming succinate--CoA ligase subunit beta -
  LPC11_RS07750 (LPC11_07750) - 1619374..1620144 (-) 771 WP_023375175.1 ribonuclease HII -
  LPC11_RS07755 (LPC11_07755) ylqF 1620137..1621012 (-) 876 WP_023375174.1 ribosome biogenesis GTPase YlqF -

Sequence

Protein


Download         Length: 289 a.a.        Molecular weight: 33731.78 Da        Isoelectric Point: 9.1427

>NTDB_id=633327 LPC11_RS07735 WP_041613962.1 1616063..1616932(-) (dprA) [Staphylococcus sp. HL28]
MNEYFLLKLYWSHFTTSQIHQFYRYNPHIFQMSSNEQETSLLCWIKQHHPTLLSKFQKYKQINIEEIMKILRQLHVKYIT
YFDEDYPYLLKEIYDYPFILFYKGDKKLFLSNQTLAIVGARKCSHYTHEALHYLFPSFKEKNITIVSGLAEGADSEAHIQ
AVKNNLPTIAVLGFGHHYYYPRTSVSLRNKIEKKGLVISEYPPFSPIAKYKFPERNRIISGLSKGVLLTEANERSGSRIT
VDCALEQNRNVYVLPGKLFDSKTKGNLLLHQEGATIVVSSEDILQDYLN

Nucleotide


Download         Length: 870 bp        

>NTDB_id=633327 LPC11_RS07735 WP_041613962.1 1616063..1616932(-) (dprA) [Staphylococcus sp. HL28]
TTGAACGAATACTTTTTACTTAAATTATACTGGTCACATTTTACAACCTCGCAAATCCATCAATTTTATCGGTACAACCC
TCATATTTTCCAAATGAGCTCTAATGAACAAGAAACCTCATTATTATGTTGGATTAAACAACATCATCCTACGCTTTTAT
CTAAATTTCAAAAATACAAACAAATAAATATAGAAGAAATTATGAAAATTCTTCGACAATTACATGTAAAATATATCACT
TATTTCGACGAGGATTATCCCTATTTATTAAAAGAAATCTATGATTATCCATTTATTCTATTTTATAAGGGAGACAAAAA
ATTATTTTTAAGTAATCAAACTTTGGCAATTGTTGGTGCTAGGAAATGTTCACATTATACGCATGAAGCACTGCATTATC
TTTTTCCTTCATTTAAAGAAAAGAATATTACGATCGTTTCTGGATTGGCAGAAGGTGCCGATAGTGAAGCACACATACAA
GCCGTGAAAAATAATTTACCAACCATTGCAGTTTTAGGGTTTGGTCATCATTATTATTATCCTAGAACGTCAGTTTCATT
AAGAAATAAAATTGAGAAAAAGGGGTTAGTTATTTCAGAATATCCACCTTTTTCGCCAATTGCTAAATATAAGTTTCCAG
AAAGAAATAGAATTATTAGTGGATTATCAAAAGGTGTCTTATTAACTGAGGCAAACGAAAGAAGCGGTAGCAGAATTACA
GTGGATTGTGCATTAGAACAAAATAGAAATGTATATGTTTTACCGGGTAAATTATTTGATTCAAAAACAAAAGGGAATTT
ATTATTACATCAAGAAGGAGCTACTATTGTCGTTAGTTCAGAAGATATTTTACAAGACTATTTAAATTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2J6P192

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

56.597

99.654

0.564
  dprA Staphylococcus aureus MW2

56.597

99.654

0.564
  dprA/cilB/dalA Streptococcus mitis SK321

36.426

100

0.367
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

36.426

100

0.367
  dprA/cilB/dalA Streptococcus pneumoniae D39

36.426

100

0.367
  dprA/cilB/dalA Streptococcus pneumoniae R6

36.426

100

0.367
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

36.426

100

0.367