Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   T15_RS00330 Genome accession   NC_022665
Coordinates   53251..54150 (+) Length   299 a.a.
NCBI ID   WP_023369017.1    Uniprot ID   -
Organism   Streptococcus suis T15     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48251..59150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  T15_RS00300 (T15_0042) - 48505..49083 (+) 579 WP_023369011.1 CPBP family intramembrane glutamic endopeptidase -
  T15_RS00305 (T15_0043) - 49098..49526 (+) 429 WP_023369013.1 Msa family membrane protein -
  T15_RS00310 - 49519..50283 (+) 765 Protein_41 ABC transporter ATP-binding protein -
  T15_RS00315 (T15_0046) ruvB 50620..51621 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  T15_RS00320 (T15_0047) - 51621..52367 (+) 747 WP_011921670.1 GNAT family N-acetyltransferase -
  T15_RS00325 (T15_0048) - 52369..53004 (+) 636 WP_023369015.1 HAD-IA family hydrolase -
  T15_RS00330 (T15_0049) comR 53251..54150 (+) 900 WP_023369017.1 helix-turn-helix domain-containing protein Regulator
  T15_RS00335 (T15_0050) - 54385..54705 (+) 321 WP_023369020.1 transposase -
  T15_RS00340 (T15_0051) - 54729..55589 (+) 861 WP_194717475.1 IS3 family transposase -
  T15_RS00350 - 56101..57039 (-) 939 Protein_48 IS4 family transposase -
  T15_RS00355 (T15_0054) - 57179..58399 (+) 1221 WP_023369028.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35443.31 Da        Isoelectric Point: 4.6526

>NTDB_id=63277 T15_RS00330 WP_023369017.1 53251..54150(+) (comR) [Streptococcus suis T15]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSSVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=63277 T15_RS00330 WP_023369017.1 53251..54150(+) (comR) [Streptococcus suis T15]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCAGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

98.328

100

0.983
  comR Streptococcus suis 05ZYH33

98.328

100

0.983
  comR Streptococcus suis D9

60.797

100

0.612
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.162

98.997

0.368

Multiple sequence alignment