Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   N4R43_RS10935 Genome accession   NZ_CP104388
Coordinates   2167595..2168965 (-) Length   456 a.a.
NCBI ID   WP_003130363.1    Uniprot ID   -
Organism   Lactococcus lactis strain LJL7m20     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2162595..2173965
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4R43_RS10920 (N4R43_10935) - 2163766..2165199 (-) 1434 WP_017864852.1 6-phospho-beta-glucosidase -
  N4R43_RS10925 (N4R43_10940) yidD 2165322..2165588 (-) 267 WP_012898265.1 membrane protein insertion efficiency factor YidD -
  N4R43_RS10930 (N4R43_10945) - 2165705..2167447 (-) 1743 WP_012898266.1 1-deoxy-D-xylulose-5-phosphate synthase -
  N4R43_RS10935 (N4R43_10950) ciaH 2167595..2168965 (-) 1371 WP_003130363.1 cell wall metabolism sensor histidine kinase WalK Regulator
  N4R43_RS10940 (N4R43_10955) ciaR 2169058..2169726 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  N4R43_RS10945 (N4R43_10960) - 2169904..2170878 (-) 975 WP_058206283.1 LacI family DNA-binding transcriptional regulator -
  N4R43_RS10950 (N4R43_10965) - 2171031..2173286 (-) 2256 WP_012898269.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51300.85 Da        Isoelectric Point: 9.4537

>NTDB_id=629264 N4R43_RS10935 WP_003130363.1 2167595..2168965(-) (ciaH) [Lactococcus lactis strain LJL7m20]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=629264 N4R43_RS10935 WP_003130363.1 2167595..2168965(-) (ciaH) [Lactococcus lactis strain LJL7m20]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAACTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAATACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTGA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTACTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCTCTGATCAAACAATTGCTAACCATATTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGACAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.837

94.298

0.461
  ciaH Streptococcus pneumoniae Rx1

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae D39

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae R6

44.321

98.465

0.436
  ciaH Streptococcus pneumoniae TIGR4

44.321

98.465

0.436