Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N1705_RS09815 Genome accession   NZ_CP104123
Coordinates   2044080..2044736 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain USDA-ARS-USMARC-49610     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2039080..2049736
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N1705_RS09785 (N1705_09785) dcyD 2039960..2040946 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  N1705_RS09790 (N1705_09790) tcyL 2040961..2041629 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N1705_RS09795 (N1705_09795) tcyN 2041626..2042378 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N1705_RS09800 (N1705_09800) sdiA 2042608..2043330 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  N1705_RS09805 (N1705_09805) yecF 2043397..2043621 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N1705_RS09810 (N1705_09810) yecU 2043608..2043784 (-) 177 WP_000590347.1 protein YecU -
  N1705_RS23350 - 2043867..2043938 (-) 72 Protein_1921 transcriptional regulator -
  N1705_RS09815 (N1705_09815) letA 2044080..2044736 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N1705_RS09820 (N1705_09820) uvrC 2044733..2046565 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N1705_RS09825 (N1705_09825) pgsA 2046622..2047170 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N1705_RS09845 (N1705_09845) yecA 2047820..2048485 (+) 666 WP_000847911.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=627337 N1705_RS09815 WP_000611335.1 2044080..2044736(+) (letA) [Escherichia coli strain USDA-ARS-USMARC-49610]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=627337 N1705_RS09815 WP_000611335.1 2044080..2044736(+) (letA) [Escherichia coli strain USDA-ARS-USMARC-49610]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486