Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LK685_RS04920 Genome accession   NZ_CP086061
Coordinates   970884..971528 (+) Length   214 a.a.
NCBI ID   WP_229762681.1    Uniprot ID   -
Organism   Bacillus sp. BC1-43     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 965884..976528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK685_RS04890 (LK685_04895) - 966271..966639 (-) 369 WP_003243784.1 hypothetical protein -
  LK685_RS04895 (LK685_04900) - 966753..966878 (-) 126 WP_003228793.1 hypothetical protein -
  LK685_RS04900 (LK685_04905) degQ 967100..967240 (+) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  LK685_RS04905 (LK685_04910) comQ 967425..968324 (+) 900 WP_003243039.1 ComX modifying isoprenyl transferase ComQ Regulator
  LK685_RS04910 (LK685_04915) comX 968312..968479 (+) 168 WP_003242801.1 competence pheromone ComX Regulator
  LK685_RS04915 (LK685_04920) comP 968494..970803 (+) 2310 WP_015251333.1 two-component system sensor histidine kinase ComP Regulator
  LK685_RS04920 (LK685_04925) comA 970884..971528 (+) 645 WP_229762681.1 two-component system response regulator ComA Regulator
  LK685_RS04925 (LK685_04930) - 971547..971927 (+) 381 WP_003228810.1 hotdog fold thioesterase -
  LK685_RS04930 (LK685_04935) mnhG 971966..972340 (-) 375 WP_003244302.1 monovalent cation/H(+) antiporter subunit G -
  LK685_RS04935 (LK685_04940) - 972324..972608 (-) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  LK685_RS04940 (LK685_04945) - 972608..973084 (-) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  LK685_RS04945 (LK685_04950) - 973090..974571 (-) 1482 WP_003244432.1 Na+/H+ antiporter subunit D -
  LK685_RS04950 (LK685_04955) - 974564..974905 (-) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  LK685_RS04955 (LK685_04960) - 974905..975336 (-) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24227.64 Da        Isoelectric Point: 4.7775

>NTDB_id=622158 LK685_RS04920 WP_229762681.1 970884..971528(+) (comA) [Bacillus sp. BC1-43]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNRMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=622158 LK685_RS04920 WP_229762681.1 970884..971528(+) (comA) [Bacillus sp. BC1-43]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATCGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

99.533

100

0.995