Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SCR2_RS08575 Genome accession   NC_022245
Coordinates   1731407..1731700 (-) Length   97 a.a.
NCBI ID   WP_003035318.1    Uniprot ID   I0SGQ0
Organism   Streptococcus constellatus subsp. pharyngis C818     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1726407..1736700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCR2_RS08555 (SCR2_1681) - 1728395..1729594 (-) 1200 WP_006267970.1 acetate kinase -
  SCR2_RS08560 (SCR2_1682) comYH 1729641..1730594 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  SCR2_RS08565 (SCR2_1683) comGG 1730679..1731005 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  SCR2_RS08570 (SCR2_1684) comGF/cglF 1730986..1731423 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCR2_RS08575 (SCR2_1685) comGE/cglE 1731407..1731700 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCR2_RS08580 (SCR2_1686) comYD 1731672..1732100 (-) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCR2_RS08585 (SCR2_1687) comYC 1732060..1732377 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SCR2_RS08590 (SCR2_1688) comYB 1732374..1733396 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCR2_RS08595 (SCR2_1689) comYA 1733338..1734279 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  SCR2_RS08600 - 1734349..1734714 (-) 366 WP_022525692.1 DUF1033 family protein -
  SCR2_RS08605 (SCR2_1690) glnA 1734902..1736248 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -
  SCR2_RS08610 (SCR2_1691) - 1736287..1736646 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10936.85 Da        Isoelectric Point: 10.4707

>NTDB_id=61848 SCR2_RS08575 WP_003035318.1 1731407..1731700(-) (comGE/cglE) [Streptococcus constellatus subsp. pharyngis C818]
MENLRKQYVRGTILLEALLASAVFAFIVTLLLGQIHQSRQTENDLLKKEEVLRVANMALQTKQSHLTINGIEVRVKKSQQ
GIQIYHGKELIVGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=61848 SCR2_RS08575 WP_003035318.1 1731407..1731700(-) (comGE/cglE) [Streptococcus constellatus subsp. pharyngis C818]
ATGGAAAATTTAAGAAAACAATACGTTAGAGGAACGATTTTATTAGAAGCTTTATTGGCATCGGCTGTTTTTGCGTTTAT
TGTGACCTTGTTATTGGGGCAGATCCATCAGTCTCGACAGACAGAAAATGATTTACTGAAAAAAGAAGAAGTTCTAAGAG
TGGCTAATATGGCATTACAAACAAAGCAAAGCCATTTAACAATAAACGGTATTGAAGTTCGTGTTAAAAAAAGTCAACAA
GGCATCCAGATTTATCATGGGAAGGAGCTGATTGTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SGQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

42.424

100

0.433
  comYE Streptococcus mutans UA159

42.424

100

0.433

Multiple sequence alignment