Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SCR2_RS08590 Genome accession   NC_022245
Coordinates   1732374..1733396 (-) Length   340 a.a.
NCBI ID   WP_037592679.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C818     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1727374..1738396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCR2_RS08555 (SCR2_1681) - 1728395..1729594 (-) 1200 WP_006267970.1 acetate kinase -
  SCR2_RS08560 (SCR2_1682) comYH 1729641..1730594 (-) 954 WP_020998065.1 class I SAM-dependent methyltransferase Machinery gene
  SCR2_RS08565 (SCR2_1683) comGG 1730679..1731005 (-) 327 WP_020998066.1 competence type IV pilus minor pilin ComGG -
  SCR2_RS08570 (SCR2_1684) comGF/cglF 1730986..1731423 (-) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  SCR2_RS08575 (SCR2_1685) comGE/cglE 1731407..1731700 (-) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  SCR2_RS08580 (SCR2_1686) comYD 1731672..1732100 (-) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  SCR2_RS08585 (SCR2_1687) comYC 1732060..1732377 (-) 318 WP_020998068.1 competence type IV pilus major pilin ComGC Machinery gene
  SCR2_RS08590 (SCR2_1688) comYB 1732374..1733396 (-) 1023 WP_037592679.1 competence type IV pilus assembly protein ComGB Machinery gene
  SCR2_RS08595 (SCR2_1689) comYA 1733338..1734279 (-) 942 WP_006268058.1 competence type IV pilus ATPase ComGA Machinery gene
  SCR2_RS08600 - 1734349..1734714 (-) 366 WP_022525692.1 DUF1033 family protein -
  SCR2_RS08605 (SCR2_1690) glnA 1734902..1736248 (-) 1347 WP_020998070.1 type I glutamate--ammonia ligase -
  SCR2_RS08610 (SCR2_1691) - 1736287..1736646 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  SCR2_RS08615 (SCR2_1692) - 1736723..1737253 (-) 531 WP_006268314.1 FUSC family protein -
  SCR2_RS08620 - 1737392..1737676 (-) 285 WP_006268247.1 2'-5' RNA ligase family protein -
  SCR2_RS08625 - 1737679..1737885 (-) 207 WP_006268044.1 hypothetical protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38877.00 Da        Isoelectric Point: 9.6572

>NTDB_id=61851 SCR2_RS08590 WP_037592679.1 1732374..1733396(-) (comYB) [Streptococcus constellatus subsp. pharyngis C818]
MQQDISLLSRQKRKKLSIVRQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEKTYVEKMKEGLATGKPFSEIMASLGFSD
SVVTQLSLAELHGNLSLSLNKIEEYLENVSTVKKKLIEVATYPFILLIFLVFIMLGLRNYLLPQLERQNSATQLISQLPQ
IFLGSLGVVLVLLAIGFYWFRKSSKIVVFSFLARLPFGGTFIQAYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWEKFFSRINQAMNLVQPLVFVFVALV
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=61851 SCR2_RS08590 WP_037592679.1 1732374..1733396(-) (comYB) [Streptococcus constellatus subsp. pharyngis C818]
ATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAGGCAGAAAAAAGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGCGGCTTTCATTTAGCAGAAATGATTGATTTTTTGAAGCGGAGTGCCCTGCTAGAAAAAA
CCTATGTGGAAAAGATGAAAGAGGGTTTAGCAACAGGAAAACCTTTTTCAGAAATTATGGCTAGTTTAGGATTTTCAGAT
AGTGTTGTCACCCAGCTTTCACTGGCAGAGCTACATGGGAATCTCTCACTCAGCCTGAATAAGATTGAGGAATACTTGGA
AAATGTCTCAACAGTCAAGAAAAAGTTAATTGAGGTAGCCACTTATCCATTCATTTTACTTATTTTTTTAGTATTCATTA
TGTTAGGGCTGCGCAATTATTTACTTCCGCAGTTAGAACGCCAAAACAGTGCAACGCAGCTGATTAGTCAGTTGCCGCAA
ATTTTTCTGGGTTCATTAGGAGTAGTCCTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCAAAAATAGT
AGTGTTTAGCTTCTTGGCTCGACTTCCTTTTGGTGGAACTTTTATTCAAGCGTATTTGACAGCTTATTATGCGCGCGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGACTTAGAAGTTGCGCTGCAAAATGGTCAGGAATTTTCCCAAGTGGTTAAACACTACCCGTTTTTTAA
AAAGGAATTGGGTTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGGTGTGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGAAGTTTTTTAGTCGGATCAATCAAGCTATGAACTTAGTACAGCCGCTTGTCTTTGTTTTTGTGGCACTGGTT
ATTGTTTTATTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.235

100

0.732
  comGB/cglB Streptococcus mitis NCTC 12261

70.03

99.118

0.694
  comGB/cglB Streptococcus mitis SK321

68.657

98.529

0.676
  comGB/cglB Streptococcus pneumoniae TIGR4

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae R6

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae Rx1

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae D39

68.358

98.529

0.674
  comYB Streptococcus mutans UA159

62.281

100

0.626
  comYB Streptococcus mutans UA140

61.988

100

0.624
  comGB Lactococcus lactis subsp. cremoris KW2

52.226

99.118

0.518

Multiple sequence alignment