Detailed information NTG0061820

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SCR2_RS04000
• Genome accession: NC_022245
• Coordinates: 801287..803515 (+)
• Length: 742 a.a.
• NCBI ID: WP_020997762.1
• Uniprot ID: -
• Organism: Streptococcus constellatus subsp. pharyngis C818
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 796287..808515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCR2_RS09975 (SCR2_0784)	rpmG	797148..797297 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
SCR2_RS03980 (SCR2_0785)	secG	797337..797570 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
SCR2_RS03985 (SCR2_0786)	rnr	797663..799799 (+)	2137	Protein_779	ribonuclease R	-
SCR2_RS03990 (SCR2_0787)	smpB	799965..800432 (+)	468	WP_006267184.1	SsrA-binding protein SmpB	-
SCR2_RS03995 (SCR2_0788)	-	800600..801303 (+)	704	Protein_781	helix-hairpin-helix domain-containing protein	-
SCR2_RS04000 (SCR2_0789)	comEC/celB	801287..803515 (+)	2229	WP_020997762.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SCR2_RS10615 (SCR2_0790)	-	803678..804082 (+)	405	WP_006267075.1	DUF805 domain-containing protein	-
SCR2_RS10620	-	804173..804313 (+)	141	WP_022525502.1	hypothetical protein	-
SCR2_RS04010 (SCR2_0791)	-	804758..805744 (+)	987	WP_020997763.1	Gfo/Idh/MocA family protein	-
SCR2_RS04015 (SCR2_0792)	-	805766..806419 (+)	654	WP_003034489.1	uracil-DNA glycosylase	-
SCR2_RS04020 (SCR2_0793)	-	806456..806926 (+)	471	WP_003031692.1	NUDIX hydrolase	-
SCR2_RS04025 (SCR2_0794)	-	806939..808216 (+)	1278	WP_020997764.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85327.29 Da
• Isoelectric Point: 9.9939

>NTDB_id=61820 SCR2_RS04000 WP_020997762.1 801287..803515(+) (comEC/celB) [Streptococcus constellatus subsp. pharyngis C818]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSSWLAWFCLIFLIVRLFVLYSPKKCFTTLMFLACFAAFFFVRREMAEWQTKA
EPSSVRQVAVLPDTIKVNGDSLSFRGKANGQTYQIYYKLKSKEEQLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQVY
LKTQGIYRNLKVDQILSSQDRVSFQPFEWLSSWRRKALVFIKRNFPNPMNHYMTGLLFGALETDFDEMSDLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLKLGLTKEMVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKVVVESSIISLGVLPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
LIFLISPFIKLIQVNFLFEGLENSIRWIANVFGRPIVFGQPSSLLLVVMLLVLAILYDVRKNKKWVILLSLCLAILFFIT
KFPLQNEITMVDVGQGDSLFLRDWKGRNVLIDVGGREEIRTKESWQKRTTKSNAEKTLIPYLKSRGIDTIDTLILTNPNA
DYAGDVLKVVKKFAVKKIFISRSSLNDADFLNKLKETKTFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKSPNQEMIERLNRLNAKIY
RTDERGAIKFSGWTKWQLETVQ

Nucleotide

• Length: 2229 bp

>NTDB_id=61820 SCR2_RS04000 WP_020997762.1 801287..803515(+) (comEC/celB) [Streptococcus constellatus subsp. pharyngis C818]
ATGTCACAGTGGATTAAGATATTTCCGATTAAACCAATTTACATTGCTTTCTTACTTGTCTGGCTATATTTTGCAATCTA
TCAAAGTAGCTGGTTGGCTTGGTTTTGTCTTATTTTTCTAATAGTCCGTCTTTTTGTCCTTTATTCACCGAAAAAATGTT
TCACAACTTTAATGTTTCTCGCTTGTTTTGCTGCTTTTTTCTTTGTTCGTAGAGAAATGGCAGAGTGGCAAACAAAAGCA
GAACCTTCTTCTGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGCGGTAA
AGCAAATGGGCAGACTTATCAAATTTACTACAAATTGAAATCAAAAGAAGAACAGTTGGCTTTTCAAAATCTATCCAGTC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGTCTAT
CTAAAAACACAAGGGATTTATCGAAATTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCTTCCAACCGTT
TGAGTGGTTGTCTAGCTGGCGAAGAAAGGCATTGGTTTTCATTAAGAGAAATTTTCCAAATCCGATGAATCATTACATGA
CAGGGCTCTTATTTGGCGCATTAGAGACAGATTTTGATGAAATGAGTGATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGTTATCTGGCATGCAAGTTGGCTTTTTTATGGAAGGATTTCGTAAGTTGCTTTTGAAGCTGGGACTTACGAAGGA
AATGGTTCATAAATGCCAATATCCGTTTTCTTTCTTTTATGCAGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAATTCAGAAATTATTGTCGCAACATGGTATCACTAAATTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTTATAGATTTTGAAAG
TCTGACTTCTTGGAGAAAAGTTGTGGTAGAGAGTAGTATCATTTCACTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GAGAATTTCAACCTTGGTCTATTTTATTGACATTTGTTTTTTCACTAATTTTTGATATAGTGATGCTACCGGGTTTAACA
CTGATTTTTCTCATTTCACCTTTCATAAAGCTCATTCAAGTAAATTTTCTTTTTGAAGGCTTAGAAAATAGTATTCGTTG
GATAGCAAATGTCTTTGGCAGACCAATCGTTTTTGGGCAACCTAGCTCGCTTTTATTAGTTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTGATATTGCTCAGCTTGTGTCTTGCTATACTATTTTTTATAACT
AAATTTCCTTTGCAAAATGAGATCACAATGGTTGATGTTGGACAGGGAGATAGTCTTTTTTTGAGAGACTGGAAAGGTAG
AAATGTATTGATTGACGTTGGAGGACGTGAAGAAATTAGAACAAAAGAATCTTGGCAAAAACGAACAACTAAATCAAATG
CGGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGTATAGATACGATTGATACTCTAATCTTAACAAATCCTAATGCA
GATTATGCGGGAGATGTATTAAAAGTGGTTAAAAAGTTTGCGGTAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAAGACGTTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAGCTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGAGCCAAAAATTCATCACATTCAAAATTTTTACAGCAAATAGAACCGGCAGTTGCACTCATTT
CTGTTGGGAAAAATAACCAATCCAAATCTCCGAATCAAGAAATGATAGAGCGATTGAATCGCTTAAATGCGAAGATTTAT
CGAACAGATGAACGAGGGGCGATCAAGTTTTCAGGATGGACAAAATGGCAATTAGAAACTGTTCAATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-577)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	54.826	100	0.551
comEC/celB	Streptococcus mitis SK321	54.752	100	0.551
comEC/celB	Streptococcus pneumoniae TIGR4	53.949	100	0.543
comEC/celB	Streptococcus pneumoniae Rx1	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae D39	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae R6	53.146	100	0.535
comEC	Lactococcus lactis subsp. cremoris KW2	46.433	100	0.465