Detailed information NTG0061815

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SCR2_RS02990
• Genome accession: NC_022245
• Coordinates: 584943..585974 (+)
• Length: 343 a.a.
• NCBI ID: WP_020997692.1
• Uniprot ID: U2ZFD1
• Organism: Streptococcus constellatus subsp. pharyngis C818
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 579943..590974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCR2_RS02965	-	580251..580565 (+)	315	WP_003073302.1	PTS cellobiose transporter subunit IIB	-
SCR2_RS02970 (SCR2_0588)	-	580621..582612 (+)	1992	WP_006267498.1	BglG family transcription antiterminator	-
SCR2_RS02975 (SCR2_0589)	-	582625..582942 (+)	318	WP_006267580.1	PTS cellobiose transporter subunit IIA	-
SCR2_RS02980 (SCR2_0590)	-	582965..583471 (+)	507	WP_020997691.1	hypothetical protein	-
SCR2_RS02985 (SCR2_0591)	celB	583511..584854 (+)	1344	WP_006267628.1	PTS cellobiose transporter subunit IIC	-
SCR2_RS02990 (SCR2_0592)	coiA	584943..585974 (+)	1032	WP_020997692.1	competence protein CoiA	Machinery gene
SCR2_RS02995 (SCR2_0593)	pepF	585926..587728 (+)	1803	WP_020997693.1	oligoendopeptidase F	Regulator
SCR2_RS03000 (SCR2_0594)	-	587729..588412 (+)	684	WP_020997694.1	O-methyltransferase	-
SCR2_RS03005 (SCR2_0595)	prsA	588519..589457 (+)	939	WP_020997695.1	peptidylprolyl isomerase PrsA	-
SCR2_RS03015 (SCR2_0596)	-	589595..590164 (+)	570	WP_080654547.1	LURP-one-related/scramblase family protein	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 40383.76 Da
• Isoelectric Point: 9.3366

>NTDB_id=61815 SCR2_RS02990 WP_020997692.1 584943..585974(+) (coiA) [Streptococcus constellatus subsp. pharyngis C818]
MLIACQENGNLLNAVEDTVNLLDKFLCPACLEAVRFKKGRVMRPHFAHISLKDCHFYTENESAEHLNLKAALFTWARKSN
HAVQVEAYLPKLQQIADLLVEKQIALEVQCSSLSQKRLKERTDSYHQHGYHVLWLLGKKLWLKDSLTNLQKDFLYFSQNM
GFYLWELDDKKQEIRLKYLIHEDLHGRAQYKVQSFPLGQGSLLTVLRTPFQRQEMTSFLAKEDKNICRYVRQQLYYQQPK
WIKLQAELYQAGDNLLTKTASDFYPQVHPVCASSFCQIFQDLTPYYQQFSAYYKKAKNKNLQVLYPPIFYAKIFGSIYDR
IGKTEEILWQNKEMKLKKNILGI

Nucleotide

• Length: 1032 bp

>NTDB_id=61815 SCR2_RS02990 WP_020997692.1 584943..585974(+) (coiA) [Streptococcus constellatus subsp. pharyngis C818]
ATGCTAATAGCTTGTCAGGAAAATGGGAACCTACTAAATGCTGTGGAAGATACGGTAAATCTGCTGGATAAATTTCTCTG
TCCAGCTTGTTTGGAGGCGGTCCGTTTTAAAAAAGGAAGAGTCATGCGACCGCATTTTGCTCATATTTCTTTAAAAGACT
GTCATTTTTATACGGAAAATGAAAGCGCAGAACACCTGAATTTGAAAGCTGCCTTGTTTACTTGGGCCAGAAAGTCTAAT
CATGCAGTTCAAGTGGAAGCGTATTTACCTAAATTGCAACAAATTGCAGATCTGTTAGTAGAGAAACAGATTGCGCTTGA
AGTTCAATGCAGTTCGCTGAGTCAAAAGCGCTTAAAAGAGCGTACGGACAGTTATCATCAGCACGGTTATCATGTTCTTT
GGCTATTAGGAAAGAAACTTTGGCTGAAAGATTCTTTAACTAATTTACAAAAAGATTTTCTTTATTTCAGTCAAAATATG
GGCTTTTATCTGTGGGAATTGGATGATAAAAAGCAGGAGATTCGGCTCAAGTATCTGATTCACGAAGATTTGCATGGCCG
AGCTCAATATAAGGTCCAGTCTTTTCCTTTGGGTCAGGGCAGCCTTTTGACTGTTCTGCGAACGCCCTTTCAACGGCAGG
AGATGACCAGTTTTCTAGCAAAAGAGGATAAAAATATTTGCCGTTATGTTCGTCAACAGCTCTATTATCAACAACCTAAA
TGGATAAAATTACAAGCAGAATTGTATCAAGCAGGTGATAATTTATTAACCAAAACGGCTAGTGACTTTTATCCGCAGGT
TCATCCGGTTTGTGCCAGCTCTTTCTGTCAAATTTTTCAAGATCTGACTCCTTATTATCAGCAATTTTCAGCTTATTATA
AAAAAGCAAAAAATAAAAATCTCCAAGTGCTCTATCCGCCAATTTTTTATGCAAAGATTTTTGGTAGTATTTATGATAGA
ATAGGAAAGACGGAGGAAATTTTATGGCAAAACAAAGAAATGAAATTGAAGAAAAATATACTTGGGATTTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (11-246)

3D structure

• AlphaFold DB: U2ZFD1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	53.185	91.545	0.487
coiA	Streptococcus mitis NCTC 12261	53.185	91.545	0.487
coiA	Streptococcus pneumoniae Rx1	52.866	91.545	0.484
coiA	Streptococcus pneumoniae D39	52.866	91.545	0.484
coiA	Streptococcus pneumoniae R6	52.866	91.545	0.484
coiA	Lactococcus lactis subsp. cremoris KW2	43.519	94.461	0.411