Detailed information NTG0615642

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: NQZ88_RS00785
• Genome accession: NZ_CP102152
• Coordinates: 123121..124158 (+)
• Length: 345 a.a.
• NCBI ID: WP_257116212.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DNS11
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118121..129158

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ88_RS00770 (NQZ88_00770)	-	120823..121188 (+)	366	WP_023369079.1	DUF1033 family protein	-
NQZ88_RS00775 (NQZ88_00775)	-	121223..122173 (-)	951	Protein_119	S66 peptidase family protein	-
NQZ88_RS00780 (NQZ88_00780)	comGA	122259..123209 (+)	951	WP_044760311.1	competence type IV pilus ATPase ComGA	Machinery gene
NQZ88_RS00785 (NQZ88_00785)	comGB	123121..124158 (+)	1038	WP_257116212.1	competence type IV pilus assembly protein ComGB	Machinery gene
NQZ88_RS00790 (NQZ88_00790)	comGC	124160..124441 (+)	282	WP_074389246.1	competence type IV pilus major pilin ComGC	Machinery gene
NQZ88_RS00795 (NQZ88_00795)	comGD	124422..124829 (+)	408	WP_074389247.1	competence type IV pilus minor pilin ComGD	Machinery gene
NQZ88_RS00800 (NQZ88_00800)	comGE	124801..125094 (+)	294	WP_024413203.1	competence type IV pilus minor pilin ComGE	Machinery gene
NQZ88_RS00805 (NQZ88_00805)	comGF/cglF	125081..125515 (+)	435	WP_074389248.1	competence type IV pilus minor pilin ComGF	Machinery gene
NQZ88_RS00810 (NQZ88_00810)	comGG	125493..125903 (+)	411	WP_074389249.1	competence type IV pilus minor pilin ComGG	-
NQZ88_RS00815 (NQZ88_00815)	-	126384..126809 (-)	426	WP_226319165.1	ArpU family phage packaging/lysis transcriptional regulator	-
NQZ88_RS00820 (NQZ88_00820)	-	127133..127708 (-)	576	WP_074392204.1	hypothetical protein	-
NQZ88_RS00825 (NQZ88_00825)	-	127729..127902 (-)	174	WP_257116213.1	hypothetical protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 38962.96 Da
• Isoelectric Point: 9.1394

>NTDB_id=615642 NQZ88_RS00785 WP_257116212.1 123121..124158(+) (comGB) [Streptococcus suis strain DNS11]
MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPVILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVGILAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide

• Length: 1038 bp

>NTDB_id=615642 NQZ88_RS00785 WP_257116212.1 123121..124158(+) (comGB) [Streptococcus suis strain DNS11]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCG
CCAGCGTAAGGTTATTGAACTGTTTAACAATCTCTTTGCTAGTGGCTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGTCAACTTTTGGCAGATCCCTATACCCAGGTCTTATCGGATGGCCTTCTTGCAGGAAAGCCGTTTTCAAGCTTATTA
GCGGATTTGCGATTTTCAGATGCAGTTGTCACGCAGGTAGCCTTAGCAGAAGTTCACGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCTTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTAATTGAGGTAGCGACCTATCCAGTTATCTTGC
TAGGTTTTCTGCTCTTGATTATGCTGGGTTTGAAAAATTACCTTCTGCCTCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTGATCAATCATCTACCGACCATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGGGATCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGATTGGACCTGCCACAGATTGTGGGCTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
CAAAACCTACGCCTTTTTTAAGCGGGAGCTGAGCCTCATCGTGGAGTATGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

• Type II secretion system (T2SS), protein F (T2SSF) (33-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus gordonii str. Challis substr. CH1	63.743	99.13	0.632
comGB/cglB	Streptococcus mitis NCTC 12261	60.896	97.101	0.591
comGB	Streptococcus mutans UA140	59.531	98.841	0.588
comGB	Streptococcus mutans UA159	59.531	98.841	0.588
comGB/cglB	Streptococcus mitis SK321	60.597	97.101	0.588
comGB/cglB	Streptococcus pneumoniae Rx1	60.299	97.101	0.586
comGB/cglB	Streptococcus pneumoniae D39	60.299	97.101	0.586
comGB/cglB	Streptococcus pneumoniae R6	60.299	97.101	0.586
comGB/cglB	Streptococcus pneumoniae TIGR4	60.299	97.101	0.586
comGB	Lactococcus lactis subsp. cremoris KW2	50.742	97.681	0.496