Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LIN98_RS00480 Genome accession   NZ_CP085096
Coordinates   98334..99557 (+) Length   407 a.a.
NCBI ID   WP_148326171.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain 4S     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 93334..104557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIN98_RS00460 nanQ 94835..95305 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  LIN98_RS00465 ampD 95779..96333 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LIN98_RS00470 pilA 96455..96907 (+) 453 WP_005586498.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LIN98_RS00475 - 96934..98341 (+) 1408 Protein_93 GspE/PulE family protein -
  LIN98_RS00480 pilC 98334..99557 (+) 1224 WP_148326171.1 type II secretion system F family protein Machinery gene
  LIN98_RS00485 - 99554..100243 (+) 690 WP_005547547.1 A24 family peptidase -
  LIN98_RS00490 coaE 100293..100916 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  LIN98_RS00495 yacG 100906..101118 (+) 213 WP_005567966.1 DNA gyrase inhibitor YacG -
  LIN98_RS00500 - 101118..101390 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  LIN98_RS00505 - 101787..103160 (+) 1374 WP_005547554.1 sodium:alanine symporter family protein -
  LIN98_RS00510 raiA 103388..103711 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  LIN98_RS00515 - 103860..104414 (+) 555 WP_005540709.1 DUF5358 domain-containing protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45944.46 Da        Isoelectric Point: 10.2664

>NTDB_id=615519 LIN98_RS00480 WP_148326171.1 98334..99557(+) (pilC) [Aggregatibacter actinomycetemcomitans strain 4S]
MIKLKLFQWRAVNRLQQKQKGLIVAETEAMAQQQLLSCGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLQAAVPLKNS
LQILLQNCTNIALNRRLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQGYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSHSLFLMLQAGIPLNQALQSFLPKQQSWQTKPQQQGDWLLIAGVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=615519 LIN98_RS00480 WP_148326171.1 98334..99557(+) (pilC) [Aggregatibacter actinomycetemcomitans strain 4S]
ATGATTAAATTGAAACTGTTTCAATGGCGCGCCGTTAATCGACTACAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGCGATGGCACAACAACAGCTGCTTTCATGCGGGTTGCAAAACATCAAATTACAACAAAACTGGCAATTTAGCCACA
AACCGAAAAATGCCGACATCTGCACGCTGCTTTCCCAACTGGCGACGCTGTTACAAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCCGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTAGCATTTTCTCAAGCATTGGAACAACAAGGTTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTTTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGGTTATTGGTTCGCGCTGCTCATGTTTATTGCACTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGCTACTTAATCGTATCGTACAACTCTCCCGTTTAGTGGGATT
CAGTCACAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTACAATCTTTCCTACCGAAACAACAAA
GCTGGCAAACTAAACCGCAGCAGCAAGGGGATTGGCTGCTTATTGCGGGAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAACAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAATTGGATCACCAAATCGATCTACTGTCAC
AAATGCTGGAACCGTTGTTGATGGTAATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTACAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

63.027

99.017

0.624
  pilC Haemophilus influenzae 86-028NP

62.283

99.017

0.617
  pilC Glaesserella parasuis strain SC1401

39.152

98.526

0.386