Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LIN92_RS10105 Genome accession   NZ_CP085089
Coordinates   2068981..2070204 (+) Length   407 a.a.
NCBI ID   WP_005567968.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain 31S     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2063981..2075204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIN92_RS10085 nanQ 2065483..2065953 (+) 471 WP_005547536.1 N-acetylneuraminate anomerase -
  LIN92_RS10090 ampD 2066427..2066981 (-) 555 WP_005567973.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LIN92_RS10095 pilA 2067103..2067555 (+) 453 WP_005586498.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LIN92_RS10100 - 2067582..2068988 (+) 1407 Protein_1947 GspE/PulE family protein -
  LIN92_RS10105 pilC 2068981..2070204 (+) 1224 WP_005567968.1 type II secretion system F family protein Machinery gene
  LIN92_RS10110 - 2070201..2070890 (+) 690 WP_005547547.1 A24 family peptidase -
  LIN92_RS10115 coaE 2070940..2071563 (+) 624 WP_005547548.1 dephospho-CoA kinase -
  LIN92_RS10120 yacG 2071553..2071765 (+) 213 WP_005567966.1 DNA gyrase inhibitor YacG -
  LIN92_RS10125 - 2071765..2072037 (+) 273 WP_005547552.1 GNAT family N-acetyltransferase -
  LIN92_RS10130 - 2072434..2073807 (+) 1374 WP_249847523.1 sodium:alanine symporter family protein -
  LIN92_RS10135 raiA 2074035..2074358 (+) 324 WP_005540708.1 ribosome-associated translation inhibitor RaiA -
  LIN92_RS10140 - 2074507..2075061 (+) 555 WP_005540709.1 DUF5358 domain-containing protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45974.49 Da        Isoelectric Point: 10.1740

>NTDB_id=615369 LIN92_RS10105 WP_005567968.1 2068981..2070204(+) (pilC) [Aggregatibacter actinomycetemcomitans strain 31S]
MIKLKLFQWRAVNRLQQKQKGLIVAETEAMAQQQLLSCGLQNIKLQQNWQFSHKPKNADICTLLSQLATLLQAAVPLKNS
LQILLQNCTNIALNRWLRCLLQEIESGLAFSQALEQQGLYLTYQERQLIQVGEMTGKLAAVCHEIAQHKQQALALQRKIQ
KILLYPLLVLGISLILTALLLLFIVPQFAAMYDNSNAQLPVFTQVLLALSQGLQGYWFALLMFIALTVALIRFRLKHSPW
LNRQKNRLINSIPLLNRIVQLSRLVGFSHSLFLMLQAGIPLNQALQSFLPKQQSWQTKPQQQGDWLLIAGVQSALHWIQQ
GYPFSASVSGQIFPPAAQQMLQVGEQSGQLPKMLQFIANDHQQQLDHQIDLLSQMLEPLLMVIIGGLIGLIMLGMYLPIF
NMGSLVQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=615369 LIN92_RS10105 WP_005567968.1 2068981..2070204(+) (pilC) [Aggregatibacter actinomycetemcomitans strain 31S]
ATGATTAAATTGAAACTGTTTCAATGGCGCGCCGTTAATCGACTACAGCAAAAACAAAAAGGCTTAATCGTGGCGGAAAC
GGAGGCGATGGCACAACAACAGCTGCTTTCATGCGGGTTGCAAAACATCAAATTACAACAAAACTGGCAATTTAGCCACA
AACCGAAAAATGCCGACATCTGCACGCTGCTTTCCCAACTGGCGACGCTGTTACAAGCCGCCGTGCCGCTGAAAAACAGC
CTGCAAATTTTATTGCAAAATTGTACCAATATTGCGTTGAATCGCTGGCTACGCTGCTTGCTACAGGAGATTGAAAGCGG
CTTAGCATTTTCTCAAGCATTGGAACAACAAGGTTTATACTTAACCTATCAGGAACGCCAACTGATTCAGGTGGGTGAAA
TGACAGGCAAACTTGCCGCCGTTTGTCATGAAATCGCACAACATAAACAACAGGCGCTGGCGTTGCAGCGTAAAATTCAG
AAAATCCTGCTTTATCCGTTGCTGGTGCTCGGAATCTCATTGATTTTGACCGCACTTTTATTGCTGTTCATCGTGCCGCA
ATTTGCCGCCATGTATGACAACAGCAACGCGCAACTGCCCGTGTTCACGCAGGTTTTACTAGCCCTTTCCCAAGGCTTGC
AGGGTTATTGGTTCGCGCTGCTCATGTTTATTGCGCTGACCGTGGCGTTAATTCGCTTTCGCCTCAAACATTCGCCTTGG
CTTAACCGACAAAAAAACCGGCTGATTAACAGTATTCCGCTACTTAATCGTATCGTACAACTCTCCCGTTTAGTGGGATT
CAGTCACAGCTTGTTTTTGATGTTACAGGCAGGTATTCCGCTGAATCAGGCGCTACAATCTTTCCTACCGAAACAACAAA
GCTGGCAAACTAAACCGCAGCAGCAAGGGGATTGGCTGCTTATTGCGGGAGTGCAATCGGCACTGCATTGGATTCAACAA
GGCTATCCGTTCTCCGCCAGCGTAAGCGGACAAATCTTCCCGCCGGCGGCACAACAAATGCTGCAAGTCGGCGAACAAAG
CGGTCAATTGCCGAAAATGCTGCAATTTATCGCCAACGATCATCAGCAACAATTGGATCACCAAATCGATCTACTGTCAC
AAATGCTGGAACCGTTGTTGATGGTAATTATCGGCGGGCTGATCGGCTTGATTATGCTCGGTATGTATTTACCGATTTTC
AACATGGGCTCGCTGGTACAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

63.275

99.017

0.627
  pilC Haemophilus influenzae 86-028NP

62.531

99.017

0.619
  pilC Glaesserella parasuis strain SC1401

39.401

98.526

0.388