Detailed information NTG0615142

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: LIO34_RS00360
• Genome accession: NZ_CP085085
• Coordinates: 59572..60489 (+)
• Length: 305 a.a.
• NCBI ID: WP_002935296.1
• Uniprot ID: -
• Organism: Streptococcus suis strain Ssuis_MA8
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	60898..62100	59572..60489	flank	409

Gene organization within MGE regions

Location: 59572..62100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LIO34_RS00360	comR	59572..60489 (+)	918	WP_002935296.1	helix-turn-helix domain-containing protein	Regulator
LIO34_RS00365	-	60898..62100 (-)	1203	WP_009909264.1	IS110-like element ISSsu7 family transposase	-

Sequence

Protein

• Length: 305 a.a.
• Molecular weight: 36252.32 Da
• Isoelectric Point: 4.6744

>NTDB_id=615142 LIO34_RS00360 WP_002935296.1 59572..60489(+) (comR) [Streptococcus suis strain Ssuis_MA8]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR

Nucleotide

• Length: 918 bp

>NTDB_id=615142 LIO34_RS00360 WP_002935296.1 59572..60489(+) (comR) [Streptococcus suis strain Ssuis_MA8]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_31) (5-60)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis D9	100	100	1
comR	Streptococcus suis P1/7	62.126	98.689	0.613
comR	Streptococcus suis 05ZYH33	62.126	98.689	0.613
comR	Streptococcus mutans UA159	37	98.361	0.364