Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EL334_RS10905 Genome accession   NZ_AP019192
Coordinates   1992183..1992665 (-) Length   160 a.a.
NCBI ID   WP_155457965.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ASP0581     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1987183..1997665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL334_RS10875 (ASP0581_20080) - 1987493..1988368 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  EL334_RS10880 (ASP0581_20090) pstC 1988486..1989349 (+) 864 WP_000595180.1 phosphate ABC transporter permease subunit PstC -
  EL334_RS10885 (ASP0581_20100) pstA 1989342..1990157 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  EL334_RS10890 (ASP0581_20110) pstB 1990159..1990911 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  EL334_RS10895 (ASP0581_20120) phoU 1990926..1991576 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  EL334_RS10900 (ASP0581_20130) - 1991617..1992060 (+) 444 Protein_2006 transposase -
  EL334_RS10905 (ASP0581_20140) comR 1992183..1992665 (-) 483 WP_155457965.1 helix-turn-helix domain-containing protein Regulator
  EL334_RS10910 (ASP0581_20150) - 1992835..1993851 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  EL334_RS10915 (ASP0581_20160) galU 1993873..1994772 (+) 900 WP_000202229.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  EL334_RS10920 (ASP0581_20170) - 1994839..1995516 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  EL334_RS10925 (ASP0581_20180) - 1995500..1996039 (-) 540 WP_000834308.1 5-formyltetrahydrofolate cyclo-ligase -
  EL334_RS10930 (ASP0581_20190) - 1996051..1997181 (-) 1131 WP_000885102.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19203.11 Da        Isoelectric Point: 4.8839

>NTDB_id=61479 EL334_RS10905 WP_155457965.1 1992183..1992665(-) (comR) [Streptococcus pneumoniae strain ASP0581]
MLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLEVEDYKLMPS
YIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 483 bp        

>NTDB_id=61479 EL334_RS10905 WP_155457965.1 1992183..1992665(-) (comR) [Streptococcus pneumoniae strain ASP0581]
ATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTT
GGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATG
GAGAATCCAGACCAACACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGT
TATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATCGC
CCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCC
CAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGG
TGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(86-133)

Helix-turn-helix (HTH_3)

(22-73)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

75

0.419
  comR Streptococcus pyogenes MGAS315

54.167

75

0.406
  comR Streptococcus mutans UA159

53.333

75

0.4
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

53.636

68.75

0.369

Multiple sequence alignment