Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SCRE_RS05685 Genome accession   NC_022236
Coordinates   1142076..1142777 (-) Length   233 a.a.
NCBI ID   WP_003035055.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1137076..1147777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS05670 (SCRE_1116) rnc 1138732..1139430 (-) 699 WP_003068697.1 ribonuclease III -
  SCRE_RS10000 - 1139566..1139831 (-) 266 Protein_1115 YbaN family protein -
  SCRE_RS05675 (SCRE_1117) vicX 1139926..1140729 (-) 804 WP_006268738.1 MBL fold metallo-hydrolase Regulator
  SCRE_RS05680 (SCRE_1118) micB 1140731..1142083 (-) 1353 WP_006268651.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SCRE_RS05685 (SCRE_1119) micA 1142076..1142777 (-) 702 WP_003035055.1 response regulator YycF Regulator
  SCRE_RS05690 (SCRE_1120) - 1143078..1143410 (-) 333 WP_006268722.1 hypothetical protein -
  SCRE_RS05695 (SCRE_1121) - 1143437..1144750 (-) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  SCRE_RS05700 (SCRE_1122) - 1144752..1145750 (-) 999 WP_020997876.1 glycosyltransferase family 4 protein -
  SCRE_RS05705 (SCRE_1123) ccpA 1145842..1146846 (-) 1005 WP_003068684.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26868.85 Da        Isoelectric Point: 4.7415

>NTDB_id=61470 SCRE_RS05685 WP_003035055.1 1142076..1142777(-) (micA) [Streptococcus constellatus subsp. pharyngis C232]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFNGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=61470 SCRE_RS05685 WP_003035055.1 1142076..1142777(-) (micA) [Streptococcus constellatus subsp. pharyngis C232]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAATTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCAATGGTCGTGAAGCATTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATCGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTAATGACGCGTGAACATCTACTAGAAACGGTGTG
GGGATATGATTATTTTGGAGATGTTCGGACTGTTGATGTGACAATTCGCCGTTTGAGAGAGAAGATTGAGGATATTCCCA
GCCGACCAGAGTATATTTTAACGCGGCGCGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

98.283

0.446
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment