Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SCRE_RS07495 Genome accession   NC_022236
Coordinates   1505805..1506494 (-) Length   229 a.a.
NCBI ID   WP_020998001.1    Uniprot ID   U2XYT2
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1500805..1511494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS07480 (SCRE_1470) nrdR 1501917..1502390 (-) 474 WP_003068126.1 transcriptional regulator NrdR -
  SCRE_RS07485 (SCRE_1471) - 1502573..1503388 (-) 816 WP_020997999.1 endonuclease/exonuclease/phosphatase family protein -
  SCRE_RS07490 (SCRE_1472) - 1503405..1505594 (-) 2190 WP_020998000.1 PTS transporter subunit IIBC -
  SCRE_RS07495 (SCRE_1473) covR 1505805..1506494 (-) 690 WP_020998001.1 DNA-binding response regulator Regulator
  SCRE_RS07500 (SCRE_1474) gndA 1506503..1507927 (-) 1425 WP_006268166.1 NADP-dependent phosphogluconate dehydrogenase -
  SCRE_RS07505 (SCRE_1475) - 1508019..1508555 (-) 537 WP_006268073.1 YceD family protein -
  SCRE_RS07510 (SCRE_1476) - 1508743..1509993 (+) 1251 WP_006268318.1 hypothetical protein -
  SCRE_RS07515 (SCRE_1477) htpX 1510062..1510958 (-) 897 WP_006268546.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26587.66 Da        Isoelectric Point: 6.1345

>NTDB_id=61475 SCRE_RS07495 WP_020998001.1 1505805..1506494(-) (covR) [Streptococcus constellatus subsp. pharyngis C232]
MGKRILLVENEKKLAQFISLELQNEGYRVDLLETGKDALTSARANQYDLFLLNFMLEDMTGTEFAEQLSLIKPASVIIVL
DNRDIILKYTEEIQRFAVSYMIEPFIVMDLVEKISAIFRGRDFIDHHCSQMKVSTSYRNLRIDVQNHTVYRGNEIISLTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKLDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=61475 SCRE_RS07495 WP_020998001.1 1505805..1506494(-) (covR) [Streptococcus constellatus subsp. pharyngis C232]
ATGGGGAAGCGGATTTTATTAGTTGAGAATGAAAAAAAATTAGCACAATTTATTAGCTTAGAGTTGCAAAATGAAGGTTA
TCGAGTGGATCTTCTTGAAACGGGAAAAGATGCTTTAACATCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGAAGATATGACAGGAACGGAGTTTGCTGAGCAATTAAGTTTGATAAAGCCTGCTTCAGTCATTATTGTATTG
GATAATCGTGATATTATTTTAAAATATACTGAGGAAATCCAACGTTTTGCTGTTAGTTATATGATAGAGCCTTTCATTGT
GATGGACTTGGTCGAAAAAATTTCTGCTATTTTTCGAGGGCGTGATTTTATCGATCATCATTGTAGTCAGATGAAAGTTT
CAACATCTTATCGGAATCTTCGCATTGACGTGCAAAATCATACTGTATATCGAGGGAATGAAATAATTTCTTTGACTAGA
AGAGAGTATGATTTGTTAGCAACGCTGATGGGCAGTCATCAGGCTTTAAGCCGTGAACAGCTGTTAGAGCGCGTTTGGAA
ATACGAAGGAGCAGTCGAAACAAATGTTGTTGATGTCTATATTCGTTATCTTCGTAGTAAACTTGATATAGCAGGGCAGA
AAAGTTACATAAAAACCGTGCGTGGTGTTGGCTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2XYT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.175

99.563

0.45

Multiple sequence alignment