Detailed information NTG0614153

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: NQD68_RS01125
• Genome accession: NZ_CP101993
• Coordinates: 189855..190316 (+)
• Length: 153 a.a.
• NCBI ID: WP_001878820.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain BCJB3344
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 184855..195316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQD68_RS01095 (NQD68_01095)	-	186470..186835 (+)	366	WP_000285373.1	DUF1033 family protein	-
NQD68_RS01100 (NQD68_01100)	comGA	187008..187979 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
NQD68_RS01105 (NQD68_01105)	comGB	187873..188916 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
NQD68_RS01110 (NQD68_01110)	comGC/cglC	188913..189242 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
NQD68_RS01115 (NQD68_01115)	comGD	189217..189630 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
NQD68_RS01120 (NQD68_01120)	comGE	189602..189901 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
NQD68_RS01125 (NQD68_01125)	comGF	189855..190316 (+)	462	WP_001878820.1	competence type IV pilus minor pilin ComGF	Machinery gene
NQD68_RS01130 (NQD68_01130)	comGG	190294..190665 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
NQD68_RS01135 (NQD68_01135)	comGH	190780..191754 (+)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
NQD68_RS01140 (NQD68_01140)	-	191786..192979 (+)	1194	WP_000047534.1	acetate kinase	-
NQD68_RS01145 (NQD68_01145)	-	193131..193337 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
NQD68_RS01150 (NQD68_01150)	-	193405..193533 (+)	129	WP_014959723.1	hypothetical protein	-
NQD68_RS01155 (NQD68_01155)	-	193574..194029 (+)	456	WP_000905673.1	hypothetical protein	-
NQD68_RS01160 (NQD68_01160)	-	194098..194763 (+)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17874.95 Da
• Isoelectric Point: 10.0299

>NTDB_id=614153 NQD68_RS01125 WP_001878820.1 189855..190316(+) (comGF) [Streptococcus agalactiae strain BCJB3344]
MKIIRKFCTYQKLRVKAFTLLKCLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=614153 NQD68_RS01125 WP_001878820.1 189855..190316(+) (comGF) [Streptococcus agalactiae strain BCJB3344]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAAAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.183	92.81	0.438
comGF	Streptococcus mutans UA140	47.183	92.81	0.438
comGF/cglF	Streptococcus pneumoniae Rx1	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae D39	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae R6	42.446	90.85	0.386
comGF/cglF	Streptococcus pneumoniae TIGR4	42.446	90.85	0.386
comGF/cglF	Streptococcus mitis SK321	43.284	87.582	0.379
comGF/cglF	Streptococcus mitis NCTC 12261	42.537	87.582	0.373
comGF	Lactococcus lactis subsp. cremoris KW2	40	91.503	0.366