Detailed information NTG0613600

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: NPS18_RS03090
• Genome accession: NZ_CP101984
• Coordinates: 602563..603501 (+)
• Length: 312 a.a.
• NCBI ID: WP_002261897.1
• Uniprot ID: Q8DV62
• Organism: Streptococcus mutans strain UA-159
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 597563..608501

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS18_RS03060 (NPS18_03060)	-	597671..598171 (+)	501	WP_002261902.1	GNAT family N-acetyltransferase	-
NPS18_RS03065 (NPS18_03065)	-	598261..599634 (-)	1374	WP_002261901.1	PLP-dependent aminotransferase family protein	-
NPS18_RS03070 (NPS18_03070)	-	599762..600730 (+)	969	WP_002261900.1	alcohol dehydrogenase catalytic domain-containing protein	-
NPS18_RS03075 (NPS18_03075)	-	600763..600890 (-)	128	Protein_571	ArsR/SmtB family transcription factor	-
NPS18_RS03080 (NPS18_03080)	-	600975..601256 (+)	282	WP_002261899.1	hypothetical protein	-
NPS18_RS03085 (NPS18_03085)	-	601362..602255 (+)	894	WP_002261898.1	alpha/beta hydrolase	-
NPS18_RS03090 (NPS18_03090)	coiA	602563..603501 (+)	939	WP_002261897.1	competence protein CoiA	Machinery gene
NPS18_RS03095 (NPS18_03095)	pepF	603523..605322 (+)	1800	WP_002261896.1	oligoendopeptidase F	Regulator
NPS18_RS03100 (NPS18_03100)	-	605535..606152 (+)	618	WP_002261895.1	HAD-IA family hydrolase	-
NPS18_RS03105 (NPS18_03105)	-	606202..606909 (+)	708	WP_002261894.1	O-methyltransferase	-
NPS18_RS03110 (NPS18_03110)	prsA	606971..607972 (+)	1002	WP_002261893.1	peptidylprolyl isomerase PrsA	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 36721.05 Da
• Isoelectric Point: 8.7637

>NTDB_id=613600 NPS18_RS03090 WP_002261897.1 602563..603501(+) (coiA) [Streptococcus mutans strain UA-159]
MLVARDKNGKLINLLNGIPDKSDFYCPACQSPVRLKNGRVMRPHFAHVALQDCKFYSENESAEHLNLKAELYQSLSQTES
VEIEKVIPEPEQIADLLVNHNLALEVQCSRLSEARLCERTQAYQANGYQVLWLLGEKLWLDRRLSNLHKQFLYFSQNMGF
HLWELDINRRELRLKYLIYEDIFGKVYYQTRSCSFDGNIMTFLQLPYAKQTLTSYPVHQRRQVGLAIQKQLLARNPRWLR
QQELAYSQGRNLIAQSDADFFPQVRLPQCSRGFCQINQDVSHFSAAFFQYYQKQKDKEIQTLYPPAFYDKMK

Nucleotide

• Length: 939 bp

>NTDB_id=613600 NPS18_RS03090 WP_002261897.1 602563..603501(+) (coiA) [Streptococcus mutans strain UA-159]
ATGTTAGTTGCAAGGGATAAAAATGGAAAGTTGATTAATCTTCTGAATGGTATTCCTGACAAAAGTGATTTTTATTGTCC
TGCCTGCCAATCACCTGTACGTCTCAAAAACGGCAGGGTTATGCGTCCGCATTTTGCCCATGTTGCTTTGCAAGACTGCA
AATTTTACAGTGAAAATGAGTCCGCTGAACACCTAAACTTGAAAGCAGAACTCTATCAGTCATTATCTCAGACGGAAAGT
GTTGAGATCGAAAAAGTCATACCAGAACCTGAACAAATCGCAGACTTATTAGTTAATCATAACCTAGCATTAGAAGTTCA
GTGTTCTCGCTTGTCCGAAGCTCGTCTGTGTGAGCGAACGCAGGCCTATCAGGCCAATGGTTATCAGGTACTGTGGCTGC
TTGGGGAGAAACTCTGGTTGGATAGGCGTTTATCCAACTTGCACAAACAATTTCTTTACTTTTCACAAAATATGGGCTTT
CATCTTTGGGAATTAGATATTAATAGGCGTGAGTTGCGACTTAAGTACTTGATTTATGAAGATATTTTTGGCAAAGTCTA
TTATCAAACGAGGTCTTGTTCTTTTGATGGTAATATCATGACCTTTTTACAATTGCCCTATGCTAAGCAAACCTTGACTT
CTTATCCTGTTCACCAGCGCAGGCAGGTTGGTTTAGCCATTCAAAAACAACTGCTAGCACGCAATCCGCGTTGGCTGCGT
CAGCAAGAACTTGCTTATTCACAGGGGCGTAATCTGATAGCACAATCAGATGCTGATTTTTTCCCGCAGGTAAGGTTACC
GCAATGTTCAAGAGGCTTTTGTCAAATCAATCAGGATGTATCTCATTTTAGCGCAGCTTTTTTTCAATATTATCAAAAGC
AAAAAGACAAAGAAATTCAAACACTGTATCCGCCAGCCTTTTATGATAAAATGAAATAA

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-263)

3D structure

• AlphaFold DB: Q8DV62

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	47.249	99.038	0.468
coiA	Streptococcus pneumoniae Rx1	46.278	99.038	0.458
coiA	Streptococcus pneumoniae D39	46.278	99.038	0.458
coiA	Streptococcus pneumoniae R6	46.278	99.038	0.458
coiA	Streptococcus pneumoniae TIGR4	45.955	99.038	0.455
coiA	Lactococcus lactis subsp. cremoris KW2	39.385	100	0.41