Detailed information NTG0612497

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: LDB25_RS18545
• Genome accession: NZ_CP084695
• Coordinates: 3683982..3685145 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain DJB5
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3678982..3690145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LDB25_RS18515 (LDB25_18440)	-	3679247..3679666 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
LDB25_RS18520 (LDB25_18445)	comFC	3679740..3680429 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
LDB25_RS18525 (LDB25_18450)	-	3680435..3680719 (-)	285	WP_014419011.1	late competence development ComFB family protein	-
LDB25_RS18530 (LDB25_18455)	comFA	3680777..3682162 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
LDB25_RS18535 (LDB25_18460)	-	3682270..3683118 (-)	849	WP_003151387.1	DegV family protein	-
LDB25_RS18540 (LDB25_18465)	degU	3683216..3683905 (-)	690	WP_111927758.1	two-component system response regulator DegU	Regulator
LDB25_RS18545 (LDB25_18470)	degS	3683982..3685145 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
LDB25_RS18550 (LDB25_18475)	-	3685368..3686015 (+)	648	WP_007614107.1	YigZ family protein	-
LDB25_RS18555 (LDB25_18480)	-	3686020..3687234 (+)	1215	WP_014419013.1	LCP family protein	-
LDB25_RS18560 (LDB25_18485)	-	3687324..3688400 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
LDB25_RS18565 (LDB25_18490)	tuaH	3688533..3689729 (-)	1197	WP_014419014.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=612497 LDB25_RS18545 WP_007407484.1 3683982..3685145(-) (degS) [Bacillus velezensis strain DJB5]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=612497 LDB25_RS18545 WP_007407484.1 3683982..3685145(-) (degS) [Bacillus velezensis strain DJB5]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951