Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EL277_RS10840 Genome accession   NZ_AP018936
Coordinates   2018788..2019270 (-) Length   160 a.a.
NCBI ID   WP_232021817.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NU83127     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2013788..2024270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS10810 (SPNU_2041) - 2014097..2014972 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  EL277_RS10815 (SPNU_2042) pstC 2015090..2015953 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  EL277_RS10820 (SPNU_2043) pstA 2015946..2016761 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  EL277_RS10825 (SPNU_2044) pstB 2016763..2017515 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  EL277_RS10830 (SPNU_2045) phoU 2017530..2018180 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  EL277_RS10835 (SPNU_2046) - 2018197..2018673 (+) 477 Protein_1996 transposase -
  EL277_RS10840 (SPNU_2047) comR 2018788..2019270 (-) 483 WP_232021817.1 helix-turn-helix domain-containing protein Regulator
  EL277_RS10845 (SPNU_2048) - 2019440..2020456 (+) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  EL277_RS10850 (SPNU_2049) galU 2020478..2021377 (+) 900 WP_000202234.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  EL277_RS10855 (SPNU_2050) - 2021795..2022736 (+) 942 WP_000428163.1 hypothetical protein -
  EL277_RS12455 - 2022838..2023023 (-) 186 WP_000693096.1 hypothetical protein -
  EL277_RS10865 (SPNU_2051) - 2023037..2023714 (-) 678 WP_000658497.1 rhomboid family intramembrane serine protease -
  EL277_RS10870 (SPNU_2052) - 2023698..2024237 (-) 540 WP_000834312.1 5-formyltetrahydrofolate cyclo-ligase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19173.13 Da        Isoelectric Point: 5.0076

>NTDB_id=61040 EL277_RS10840 WP_232021817.1 2018788..2019270(-) (comR) [Streptococcus pneumoniae strain NU83127]
MLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLGVEDYKLMPS
YIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 483 bp        

>NTDB_id=61040 EL277_RS10840 WP_232021817.1 2018788..2019270(-) (comR) [Streptococcus pneumoniae strain NU83127]
ATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTT
GGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATG
GAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGGGGTTGAAGATTACAAGTTGATGCCAAGT
TATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATCGC
CCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCC
CAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGG
TGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(86-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

75

0.419
  comR Streptococcus pyogenes MGAS315

54.167

75

0.406
  comR Streptococcus mutans UA159

53.333

75

0.4
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.545

68.75

0.375

Multiple sequence alignment