Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   EL269_RS11225 Genome accession   NZ_AP018935
Coordinates   2155413..2156003 (-) Length   196 a.a.
NCBI ID   WP_000272487.1    Uniprot ID   Q8DWW6
Organism   Streptococcus agalactiae strain HU-GS5823     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2150413..2161003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL269_RS11190 (SAGS_2137) - 2150433..2150750 (-) 318 WP_000940932.1 DUF1292 domain-containing protein -
  EL269_RS11195 (SAGS_2138) ruvX 2150776..2151195 (-) 420 WP_001222109.1 Holliday junction resolvase RuvX -
  EL269_RS11200 (SAGS_2139) - 2151195..2151461 (-) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  EL269_RS11205 (SAGS_2140) spx 2151663..2152061 (-) 399 WP_000591161.1 transcriptional regulator Spx -
  EL269_RS11210 (SAGS_2141) recA 2152277..2153416 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  EL269_RS11215 - 2153490..2154750 (-) 1261 Protein_2070 competence/damage-inducible protein A -
  EL269_RS11220 (SAGS_2144) - 2154839..2155390 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  EL269_RS11225 (SAGS_2145) ruvA 2155413..2156003 (-) 591 WP_000272487.1 Holliday junction branch migration protein RuvA Machinery gene
  EL269_RS11230 - 2156005..2157237 (-) 1233 Protein_2073 MFS transporter -
  EL269_RS11235 (SAGS_2148) hexB 2157269..2159242 (-) 1974 WP_000034617.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL269_RS11245 (SAGS_2149) - 2159468..2159671 (+) 204 WP_000191849.1 cold-shock protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21729.00 Da        Isoelectric Point: 5.7488

>NTDB_id=60930 EL269_RS11225 WP_000272487.1 2155413..2156003(-) (ruvA) [Streptococcus agalactiae strain HU-GS5823]
MYDYIKGKLSKITAKFIVVETAGLGYMIYVANPYSFSGYVNQEVTIYLHQVIRDDAHLLFGFHTENEKEIFLNLISVSGI
GPTTALAIIAVDDNEGLVSAIDNSDIKYLTKFPKIGKKTAQQMILDLSGKFVEASGESATSRKVSSEQNSNLEEAMEALL
ALGYKATELKKVKAFFEGTNETVEQYIKSSLKMLMK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=60930 EL269_RS11225 WP_000272487.1 2155413..2156003(-) (ruvA) [Streptococcus agalactiae strain HU-GS5823]
ATGTACGATTATATTAAAGGAAAATTGAGTAAAATAACGGCTAAATTTATTGTTGTGGAAACAGCTGGATTGGGATACAT
GATATATGTGGCAAATCCCTACTCTTTTTCAGGTTACGTTAATCAAGAAGTTACCATCTACTTACATCAAGTCATTCGCG
ATGATGCACATCTTTTATTTGGCTTTCATACGGAAAATGAAAAAGAAATTTTTCTTAATTTAATTTCAGTATCAGGAATT
GGTCCAACGACCGCTTTAGCAATTATTGCAGTCGATGACAATGAAGGTCTCGTAAGTGCCATTGATAATAGTGATATTAA
GTATTTGACTAAATTTCCAAAGATAGGAAAAAAAACAGCACAACAGATGATCCTTGATTTGTCAGGGAAGTTTGTAGAAG
CTTCTGGTGAGAGTGCGACTAGTCGTAAGGTTAGCTCTGAGCAGAATAGCAATCTTGAAGAAGCTATGGAAGCTTTGTTA
GCGTTGGGGTATAAGGCGACTGAATTGAAAAAAGTAAAAGCCTTTTTTGAAGGTACGAACGAGACTGTGGAGCAATACAT
CAAATCTAGTTTGAAGATGTTGATGAAATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(151-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DWW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae R6

67.513

100

0.679
  ruvA Streptococcus pneumoniae D39

67.513

100

0.679
  ruvA Streptococcus pneumoniae TIGR4

67.005

100

0.673
  ruvA Bacillus subtilis subsp. subtilis str. 168

39.409

100

0.408

Multiple sequence alignment