Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KE3_RS08165 Genome accession   NC_021900
Coordinates   1623814..1624506 (-) Length   230 a.a.
NCBI ID   WP_020917358.1    Uniprot ID   A0AB33ANI4
Organism   Streptococcus lutetiensis 033     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1618814..1629506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS08145 (KE3_1682) dnaI 1619618..1620520 (-) 903 WP_020917355.1 primosomal protein DnaI -
  KE3_RS08150 (KE3_1683) - 1620531..1621682 (-) 1152 WP_020917356.1 DnaD domain protein -
  KE3_RS08155 (KE3_1684) nrdR 1621669..1622163 (-) 495 WP_006532915.1 transcriptional regulator NrdR -
  KE3_RS08160 (KE3_1685) - 1622345..1623814 (-) 1470 WP_020917357.1 HAMP domain-containing histidine kinase -
  KE3_RS08165 (KE3_1686) covR 1623814..1624506 (-) 693 WP_020917358.1 response regulator transcription factor Regulator
  KE3_RS08170 (KE3_1687) - 1624747..1625283 (-) 537 WP_043895103.1 YceD family protein -
  KE3_RS08175 (KE3_1688) htpX 1625425..1626324 (-) 900 WP_020917360.1 zinc metalloprotease HtpX -
  KE3_RS08180 (KE3_1689) - 1626437..1626988 (-) 552 WP_020917361.1 LemA family protein -
  KE3_RS08185 (KE3_1690) rsmG 1627282..1627995 (+) 714 WP_020917362.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  KE3_RS08190 (KE3_1691) - 1628061..1629434 (+) 1374 WP_043895104.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26356.30 Da        Isoelectric Point: 4.8466

>NTDB_id=60838 KE3_RS08165 WP_020917358.1 1623814..1624506(-) (covR) [Streptococcus lutetiensis 033]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQAKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=60838 KE3_RS08165 WP_020917358.1 1623814..1624506(-) (covR) [Streptococcus lutetiensis 033]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTTGTGTCTTTAGAATTACAACATGAGGGGTA
TTCAGTAGTTGTTGAGACAAATGGACGTTTAGGGCTTCAAACAGCATTGGATGATGATTTTGATTTGATCCTATTAGATT
TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGCTTGGAAAAAGATACATCAATTATCATGATGACT
GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTTGACCGTGGAGCAGATGATTACATTGTAAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGCAAAAGAAGGTCAAGCAAAAG
AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCGGCAGTGCGTGGAGATGATGAAATTTCATTAACAAAACGT
GAATACGACTTGTTGAGCGTGCTTCTTTCAAATGTTAATCGCGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG
TTATGATACAGACATCGAAACAAATGTCGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

77.056

100

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417

Multiple sequence alignment