Detailed information NTG0060820

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: KE3_RS03050
• Genome accession: NC_021900
• Coordinates: 565193..567427 (+)
• Length: 744 a.a.
• NCBI ID: WP_043894997.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis 033
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 560193..572427

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KE3_RS03025 (KE3_0614)	-	560934..562511 (+)	1578	WP_020916419.1	DEAD/DEAH box helicase	-
KE3_RS03030 (KE3_0615)	-	562552..562827 (-)	276	WP_020916420.1	GIY-YIG nuclease family protein	-
KE3_RS03035 (KE3_0616)	-	562802..563563 (-)	762	WP_020916421.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
KE3_RS03040 (KE3_0617)	-	563679..564425 (+)	747	WP_043894996.1	lysophospholipid acyltransferase family protein	-
KE3_RS03045 (KE3_0618)	-	564523..565203 (+)	681	WP_020916423.1	helix-hairpin-helix domain-containing protein	-
KE3_RS03050 (KE3_0619)	comEC/celB	565193..567427 (+)	2235	WP_043894997.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
KE3_RS03055 (KE3_0620)	holA	567492..568529 (+)	1038	WP_020916425.1	DNA polymerase III subunit delta	-
KE3_RS03060 (KE3_0621)	-	568624..569235 (+)	612	WP_020916426.1	superoxide dismutase	-
KE3_RS03065 (KE3_0622)	-	569337..570062 (+)	726	WP_043894998.1	YebC/PmpR family DNA-binding transcriptional regulator	-
KE3_RS03070 (KE3_0623)	queA	570113..571141 (-)	1029	WP_020916428.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
KE3_RS03075 (KE3_0624)	-	571305..571811 (+)	507	WP_020916429.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84241.65 Da
• Isoelectric Point: 8.6678

>NTDB_id=60820 KE3_RS03050 WP_043894997.1 565193..567427(+) (comEC/celB) [Streptococcus lutetiensis 033]
MLIKHFPVKPIQLAFLLILLYYFCFSKGIGCLMFLLLALLFLWQQYGWKAWYQVSLCLAFFAIFFLTKANQTEQAYQAAP
TQLAKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYILKSEKEQEFFKNLNQTMLLSGQVDLEEATPQRNFGGFDYRTYLK
HEGIYRIANLSSITEIRQQSSLSFFERLHELRRQAIVSIQRNFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFA
LSGMQVGFFVALFRFIILRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLAFTLMTLFILMP
NFLLTTGGILSFTYAFILSFIDFDELSHYQKILTECFAISLGSLPVLLYFFSVFQPLSLLLTAIFSLAFDTLILPVLTFV
FLLSPLVKITALNPFFVFLETIIKFSKSLIGTPLVFGRPSLGILLLLLLIIGLLYDCYRHKKVAIFLFSIIALLFFQIKH
PLENEVTVVDIGQGDSILVRDVKGQTLLIDVGGKVRFSEKKSWQKRLADSNAERTLIPYLKSRGIGKIDQLVLTHTDTDH
MGDMLEVAKELKIGQVLVSPGSLTKPDFVVKLRQMKTPVHAVSAGDNLPIMGSHLQVLYPNAVGDGGNNDSVVLYGNLLG
KNFLFTGDLEEEGEEQMMATYPNLPVDVLKAGHHGSKGSSSPEFLDHISPQMALISAGQNNRYKHPHQETLDRFQNQNMT
IYRTDQQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=60820 KE3_RS03050 WP_043894997.1 565193..567427(+) (comEC/celB) [Streptococcus lutetiensis 033]
CTGTTGATTAAGCATTTCCCTGTCAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAA
AGGGATTGGGTGTTTGATGTTTCTCTTGCTAGCTTTGCTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTATCAGG
TTTCACTGTGTTTGGCTTTTTTTGCGATATTTTTCCTGACTAAGGCTAATCAGACAGAACAGGCTTATCAAGCGGCGCCA
ACTCAGCTAGCAAAAATACAGATGATTCCAGATACGATTTCGGTTAATGGTGATTTGTTATCTTTTCGAGGGAAGGAGGC
TGGGCAGACTTACCAAGTTTTTTATATCTTGAAGTCAGAAAAAGAGCAGGAATTTTTTAAAAATCTTAATCAAACAATGC
TTTTATCAGGGCAGGTGGATCTAGAAGAGGCAACGCCACAACGGAATTTTGGTGGTTTTGATTACCGCACTTACCTTAAA
CATGAAGGCATTTATCGGATTGCTAATCTTTCTTCGATTACTGAAATAAGACAGCAGAGCTCTTTAAGTTTTTTTGAACG
ACTACATGAACTTAGAAGACAGGCGATTGTCAGTATTCAAAGGAATTTTCCTGCTCCCATGCAACATTACATGACTGGCC
TTTTGTTTGGATATTTGGATAAGTCTTTTGATGAGATGAGTGATGTTTATACTAGTTTAGGGATTATTCATCTTTTTGCT
CTGTCTGGTATGCAGGTAGGCTTTTTTGTGGCACTTTTTCGTTTTATTATTTTACGTCTTGGGTTACGGCGAGATTATGT
GGATATACTGCAAATCCCGTTTTCACTTGTATATGCTGGCTTGACAGGCTTTTCGGTATCAGTGATTCGTAGTTTAATTC
AGTCTGCCTTTGCAAATCTTGGTATTAAAAAATTAGATAATCTTGCCTTTACTTTAATGACCCTTTTTATTTTGATGCCA
AATTTCCTGCTAACAACAGGAGGAATTCTTTCTTTTACCTACGCTTTCATCCTGAGTTTTATTGATTTTGATGAGCTTAG
TCATTATCAAAAAATCCTTACAGAATGTTTTGCGATTTCGCTGGGAAGTTTACCGGTTTTGCTATATTTCTTCTCAGTAT
TTCAACCTTTGTCGCTGCTTTTAACAGCTATTTTTTCACTAGCTTTTGATACGCTTATCTTACCTGTTTTGACCTTTGTT
TTTCTTTTATCACCTCTGGTTAAAATTACCGCGTTAAATCCATTTTTTGTTTTTTTGGAAACTATCATCAAATTTAGTAA
GTCGCTGATTGGCACACCACTTGTTTTTGGCAGACCAAGTCTAGGAATTTTGTTGCTATTACTTTTAATAATAGGACTTC
TCTATGACTGTTATCGACACAAAAAAGTGGCCATTTTCCTTTTTAGCATAATAGCTTTGCTATTTTTCCAAATCAAGCAT
CCGCTCGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGCATTTTGGTGCGAGATGTAAAGGGGCAGACGCT
GTTAATTGATGTCGGAGGAAAAGTGAGGTTTAGTGAGAAAAAATCGTGGCAAAAGCGCTTAGCTGATAGCAATGCTGAGC
GGACATTGATTCCTTATCTGAAAAGTCGAGGAATTGGTAAAATTGATCAGTTAGTTTTGACGCACACGGATACCGACCAT
ATGGGCGATATGCTGGAAGTCGCAAAAGAGCTGAAAATTGGTCAAGTCCTGGTGAGTCCAGGAAGTCTCACAAAGCCAGA
TTTTGTGGTTAAACTTCGACAAATGAAGACGCCAGTTCACGCAGTTTCTGCAGGAGATAACTTGCCAATTATGGGAAGTC
ACTTGCAGGTGCTTTATCCGAATGCTGTTGGTGATGGTGGAAATAATGATTCTGTGGTGCTTTATGGTAATCTTCTGGGT
AAGAATTTCTTGTTTACTGGAGACTTGGAAGAAGAGGGCGAAGAGCAGATGATGGCAACTTATCCCAATCTGCCAGTCGA
TGTCTTAAAAGCAGGACATCACGGTTCAAAAGGGTCATCGAGCCCAGAATTTCTAGATCACATTTCACCACAAATGGCTT
TGATTTCCGCAGGGCAAAATAACCGTTACAAACACCCTCACCAAGAAACACTTGATCGTTTTCAAAATCAAAATATGACC
ATTTACCGCACAGACCAACAAGGTGCTATCCGTTTTAGAGGATTAAACCACTGGAAAATTGAAACGGTGAGGTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-175)

• Competence protein (Competence) (214-455)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-686)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	50.809	99.731	0.507
comEC/celB	Streptococcus mitis NCTC 12261	50.809	99.731	0.507
comEC/celB	Streptococcus pneumoniae TIGR4	49.933	99.866	0.499
comEC/celB	Streptococcus pneumoniae Rx1	49.394	99.866	0.493
comEC/celB	Streptococcus pneumoniae D39	49.394	99.866	0.493
comEC/celB	Streptococcus pneumoniae R6	49.394	99.866	0.493
comEC	Lactococcus lactis subsp. cremoris KW2	47.46	100	0.477