NTDB

Overview

Name	comE	Type	Machinery gene
Locus tag	NMD37_RS01880	Genome accession	NZ_CP100966
Coordinates	415977..417215 (+)	Length	412 a.a.
NCBI ID	WP_137482110.1	Uniprot ID	-
Organism	Escherichia coli strain ET350
Function	type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 410977..422215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMD37_RS01855 (NMD37_01845)	mrcA	411257..413809 (-)	2553	WP_001301905.1	peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA	-
NMD37_RS01860 (NMD37_01850)	hofM	413929..414708 (+)	780	WP_001308095.1	DNA utilization protein HofM	-
NMD37_RS01865 (NMD37_01855)	hofN	414708..415247 (+)	540	WP_001069342.1	DNA utilization protein HofN	-
NMD37_RS01870 (NMD37_01860)	hofO	415231..415671 (+)	441	WP_001055738.1	DNA utilization protein HofO	-
NMD37_RS01875 (NMD37_01865)	hofP	415661..416065 (+)	405	WP_032218504.1	DNA utilization protein HofP	-
NMD37_RS01880 (NMD37_01870)	comE	415977..417215 (+)	1239	WP_137482110.1	DNA uptake porin HofQ	Machinery gene
NMD37_RS01885 (NMD37_01875)	aroK	417616..418137 (+)	522	WP_000818618.1	shikimate kinase AroK	-
NMD37_RS01890 (NMD37_01880)	aroB	418194..419282 (+)	1089	WP_000439848.1	3-dehydroquinate synthase	-
NMD37_RS01895 (NMD37_01885)	damX	419374..420660 (+)	1287	WP_000343210.1	cell division protein DamX	-
NMD37_RS01900 (NMD37_01890)	dam	420767..421603 (+)	837	WP_000742141.1	adenine-specific DNA-methyltransferase	-

Sequence

Protein

Download Length: 412 a.a. Molecular weight: 44749.26 Da Isoelectric Point: 5.9488

                                >NTDB_id=607908 NMD37_RS01880 WP_137482110.1 415977..417215(+) (comE) [Escherichia coli strain ET350]

MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGL

ITRQEGNILSVHSIAWQNDNIARQEAEQARAQANLPLENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN

KTALSALEQWLAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQQAGGVGQVTTLGSDLSVATATTHVGFNIGRIN

GRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKL

HISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERREL

VVFITPRLVSSE

Nucleotide

Download Length: 1239 bp

                                >NTDB_id=607908 NMD37_RS01880 WP_137482110.1 415977..417215(+) (comE) [Escherichia coli strain ET350]

ATGAAGCAATGGATAGCCGCACTACTGTTGATGCTGATACCCGGCGTACAGGCGGCAAAGCCGCAAAAAGTGACGCTGAT

GGTGGATGACGTTCCGGTAGCTCAGGTGTTGCAGGCGCTGGCTGAACAGGAGAAGTTGAACCTGGTGGTGTCGCCAGACG

TCAGCGGTACGGTGTCGTTACATCTAACAGATGTTCCCTGGAAGCAGGCACTACAAACTGTAGTGAAAAGCGCCGGACTG

ATAACGCGCCAGGAGGGCAACATTCTCTCAGTGCATTCCATTGCCTGGCAGAATGACAATATCGCCCGTCAGGAAGCGGA

GCAGGCGCGGGCGCAGGCAAATCTGCCGCTGGAAAATCGCAATATTACTCTGCAATACGCCGACGCCGGAGAGCTGGCGA

AAGCTGGGGAAAAGCTACTGAGTGCCAAAGGGAGTATGACCGTCGATAAACGCACCAATCGCCTTTTGCTGCGAGATAAC

AAAACGGCGTTAAGCGCACTTGAACAGTGGCTAGCGCAAATGGATCTGCCGGTCGGGCAGGTTGAGCTGTCGGCGCATAT

TGTCACCATTAATGAAAAAAGTTTGCGTGAGTTAGGCGTGAAATGGACGCTGGCCGATGCGCAACAAGCTGGGGGCGTTG

GGCAAGTCACCACGCTTGGTAGCGACCTCTCCGTAGCGACGGCGACAACGCATGTCGGTTTTAACATTGGGCGCATCAAC

GGACGTTTGCTGGATCTTGAGCTTTCCGCGCTCGAACAAAAACAGCAGCTGGATATTATCGCCAGTCCGCGTCTGCTGGC

CTCACATCTTCAGCCTGCCAGCATTAAACAGGGGAGCGAAATTCCATATCAGGTTTCCAGCGGGGAAAGTGGCGCGACGT

CGGTGGAATTTAAAGAGGCCGTCCTGGGGATGGAGGTCACGCCCACGGTGTTACAAAAAGGTCGCATTCGGCTGAAATTA

CACATCAGCCAGAACGTTCCGGGGCAGGTGCTACAGCAGGCCGATGGCGAAGTGCTGGCGATTGATAAGCAGGAGATTGA

AACGCAGGTCGAGGTCAAAAGCGGAGAAACGTTGGCGCTGGGCGGCATTTTTACCCGTAAAAATAAATCGGGTCAGGATA

GCGTGCCGTTGCTTGGCGACATTCCCTGGTTCGGGCAATTATTTCGTCATGACGGAAAAGAAGATGAACGACGCGAGTTA

GTGGTGTTTATCACGCCACGACTGGTTTCCAGTGAGTAA

Domains

Predicted by InterProScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(120-178)

Bacterial type II and III secretion system protein (Secretin)

(250-409)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE	Haemophilus influenzae Rd KW20	37.156	100	0.393
comE	Haemophilus influenzae 86-028NP	36.927	100	0.391
pilQ	Vibrio campbellii strain DS40M4	38.242	100	0.391
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	37.772	100	0.379
pilQ	Vibrio cholerae strain A1552	37.772	100	0.379
comE	Glaesserella parasuis strain SC1401	35.714	100	0.364

Detailed information NTG0607908