Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   N220_RS11570 Genome accession   NC_021883
Coordinates   2296802..2297140 (+) Length   112 a.a.
NCBI ID   WP_006251644.1    Uniprot ID   A0A248ZWT2
Organism   Mannheimia haemolytica USMARC_2286     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2291802..2302140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N220_RS11545 (N220_12075) rpsL 2292041..2292415 (-) 375 WP_005543325.1 30S ribosomal protein S12 -
  N220_RS11550 (N220_12080) rfaC 2292536..2293495 (-) 960 WP_006250332.1 lipopolysaccharide heptosyltransferase RfaC -
  N220_RS11555 (N220_12085) waaF 2293562..2294599 (-) 1038 WP_006250331.1 lipopolysaccharide heptosyltransferase II -
  N220_RS11560 (N220_12090) - 2294710..2295126 (-) 417 WP_006250330.1 MliC family protein -
  N220_RS11565 (N220_12095) - 2295190..2296509 (-) 1320 WP_006253337.1 LysM-like peptidoglycan-binding domain-containing protein -
  N220_RS11570 (N220_12100) comEA/comE1 2296802..2297140 (+) 339 WP_006251644.1 ComEA family DNA-binding protein Machinery gene
  N220_RS11575 (N220_12105) asd 2297305..2298198 (+) 894 WP_006250004.1 archaetidylserine decarboxylase -
  N220_RS11580 (N220_12110) - 2298270..2300621 (+) 2352 WP_006250003.1 DEAD/DEAH box helicase family protein -
  N220_RS11585 (N220_12115) - 2300669..2302138 (+) 1470 WP_006250002.1 class I SAM-dependent DNA methyltransferase -

Sequence

Protein


Download         Length: 112 a.a.        Molecular weight: 12111.91 Da        Isoelectric Point: 10.0993

>NTDB_id=60694 N220_RS11570 WP_006251644.1 2296802..2297140(+) (comEA/comE1) [Mannheimia haemolytica USMARC_2286]
MKKIKQLGLTFLFGLNAMAFAQTPPTTMPVEQNAVTQPVQQTQITNANAVNINTASAAELQDKLVGIGQKKAQAIVDYRT
KNGNFKNIEQLAEVSGIGQATVEKNRANIILE

Nucleotide


Download         Length: 339 bp        

>NTDB_id=60694 N220_RS11570 WP_006251644.1 2296802..2297140(+) (comEA/comE1) [Mannheimia haemolytica USMARC_2286]
ATGAAGAAAATCAAACAACTTGGTCTAACATTCTTGTTTGGCTTAAATGCAATGGCTTTTGCCCAAACACCGCCAACTAC
AATGCCTGTTGAACAAAATGCAGTCACTCAACCCGTACAGCAAACACAAATCACCAACGCTAATGCGGTAAATATCAATA
CTGCTAGTGCTGCTGAATTGCAAGACAAGCTAGTGGGAATTGGGCAGAAAAAAGCTCAAGCGATTGTCGATTACCGTACT
AAAAACGGCAATTTTAAAAACATTGAGCAACTTGCTGAAGTCTCCGGAATTGGGCAAGCAACGGTAGAAAAAAATCGAGC
CAATATTATTTTAGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(46-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A248ZWT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

59.292

100

0.598
  comE1/comEA Haemophilus influenzae Rd KW20

52.747

81.25

0.429
  comEA Vibrio cholerae C6706

54.651

76.786

0.42
  comEA Vibrio cholerae strain A1552

54.651

76.786

0.42

Multiple sequence alignment