Detailed information NTG0606819

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: LA346_RS03825
• Genome accession: NZ_CP083627
• Coordinates: 702541..703002 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FDAARGOS_1508
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 697541..708002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA346_RS03795 (LA346_03795)	-	697848..698672 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
LA346_RS03800 (LA346_03800)	rnpA	698647..699018 (-)	372	WP_000739246.1	ribonuclease P protein component	-
LA346_RS10825	-	699035..699166 (-)	132	WP_000768904.1	hypothetical protein	-
LA346_RS03805 (LA346_03805)	-	699167..700357 (-)	1191	WP_000167765.1	acetate kinase	-
LA346_RS03810 (LA346_03810)	comYH	700408..701361 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
LA346_RS03815 (LA346_03815)	-	701422..702014 (-)	593	Protein_731	class I SAM-dependent methyltransferase	-
LA346_RS03820 (LA346_03820)	comGG/cglG	702117..702563 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
LA346_RS03825 (LA346_03825)	comGF/cglF	702541..703002 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
LA346_RS03830 (LA346_03830)	comGE/cglE	702965..703267 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
LA346_RS03835 (LA346_03835)	comGD/cglD	703230..703664 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
LA346_RS03840 (LA346_03840)	comGC/cglC	703627..703950 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
LA346_RS03845 (LA346_03845)	comGB/cglB	703952..704968 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
LA346_RS03850 (LA346_03850)	comGA/cglA/cilD	704916..705857 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
LA346_RS03855 (LA346_03855)	-	705933..706298 (-)	366	WP_000286415.1	DUF1033 family protein	-
LA346_RS03860 (LA346_03860)	-	706449..707507 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=606819 LA346_RS03825 WP_000250531.1 702541..703002(-) (comGF/cglF) [Streptococcus pneumoniae strain FDAARGOS_1508]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=606819 LA346_RS03825 WP_000250531.1 702541..703002(-) (comGF/cglF) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915