Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   LA346_RS02555 Genome accession   NZ_CP083627
Coordinates   476951..477610 (+) Length   219 a.a.
NCBI ID   WP_000564991.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FDAARGOS_1508     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 471951..482610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA346_RS02530 (LA346_02530) - 472256..472573 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  LA346_RS02535 (LA346_02535) - 472588..473484 (-) 897 WP_000825665.1 PEP phosphonomutase -
  LA346_RS02540 (LA346_02540) - 473481..474749 (-) 1269 WP_000413337.1 PTS sugar transporter subunit IIC -
  LA346_RS02545 (LA346_02545) - 475029..476207 (+) 1179 WP_000175879.1 ROK family transcriptional regulator -
  LA346_RS02550 (LA346_02550) - 476435..476881 (-) 447 WP_000155412.1 GNAT family N-acetyltransferase -
  LA346_RS02555 (LA346_02555) cclA/cilC 476951..477610 (+) 660 WP_000564991.1 A24 family peptidase Machinery gene
  LA346_RS02560 (LA346_02560) - 477662..478813 (-) 1152 WP_000481750.1 ImmA/IrrE family metallo-endopeptidase -
  LA346_RS02565 (LA346_02565) - 478828..479559 (-) 732 WP_000934018.1 hypothetical protein -
  LA346_RS02570 (LA346_02570) - 479785..479889 (+) 105 Protein_515 prepilin peptidase -
  LA346_RS02575 (LA346_02575) trpA 479861..480637 (-) 777 WP_001127044.1 tryptophan synthase subunit alpha -
  LA346_RS02580 (LA346_02580) trpB 480630..481853 (-) 1224 WP_000331294.1 tryptophan synthase subunit beta -
  LA346_RS02585 (LA346_02585) - 481831..482430 (-) 600 WP_000169912.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24880.03 Da        Isoelectric Point: 7.9671

>NTDB_id=606798 LA346_RS02555 WP_000564991.1 476951..477610(+) (cclA/cilC) [Streptococcus pneumoniae strain FDAARGOS_1508]
MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=606798 LA346_RS02555 WP_000564991.1 476951..477610(+) (cclA/cilC) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGAA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae Rx1

95.434

100

0.954
  cclA/cilC Streptococcus pneumoniae D39

95.434

100

0.954
  cclA/cilC Streptococcus pneumoniae R6

95.434

100

0.954
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

85.388

100

0.854