Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   K748_RS04005 Genome accession   NC_021882
Coordinates   813575..814318 (+) Length   247 a.a.
NCBI ID   WP_015645815.1    Uniprot ID   -
Organism   Helicobacter pylori UM298     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 808575..819318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K748_RS03980 (K748_05420) panD 810725..811075 (+) 351 WP_015645812.1 aspartate 1-decarboxylase -
  K748_RS03985 (K748_05425) - 811086..811379 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  K748_RS03990 (K748_05430) - 811379..812374 (+) 996 WP_015645813.1 PDZ domain-containing protein -
  K748_RS03995 (K748_05435) comB6 812382..813437 (+) 1056 WP_015645814.1 P-type conjugative transfer protein TrbL Machinery gene
  K748_RS04000 comB7 813453..813578 (+) 126 WP_020849792.1 hypothetical protein Machinery gene
  K748_RS04005 (K748_05445) comB8 813575..814318 (+) 744 WP_015645815.1 virB8 family protein Machinery gene
  K748_RS04010 (K748_05450) comB9 814318..815313 (+) 996 WP_015645816.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  K748_RS04015 (K748_05455) comB10 815306..816442 (+) 1137 WP_015645817.1 DNA type IV secretion system protein ComB10 Machinery gene
  K748_RS04020 (K748_05460) - 816508..817920 (+) 1413 WP_015645818.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  K748_RS04025 (K748_05465) gmd 817935..819080 (+) 1146 WP_015645819.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28726.99 Da        Isoelectric Point: 8.9546

>NTDB_id=60672 K748_RS04005 WP_015645815.1 813575..814318(+) (comB8) [Helicobacter pylori UM298]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=60672 K748_RS04005 WP_015645815.1 813575..814318(+) (comB8) [Helicobacter pylori UM298]
ATGAAGGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTATTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCTATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAGTTGGTATATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCAGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCACCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.976

100

0.98

Multiple sequence alignment