Detailed information    

insolico Bioinformatically predicted

Overview

Name   tfoX   Type   Regulator
Locus tag   HK81_RS15235 Genome accession   NC_021848
Coordinates   1587283..1587870 (-) Length   195 a.a.
NCBI ID   WP_005459593.1    Uniprot ID   Q87QA8
Organism   Vibrio parahaemolyticus O1:K33 str. CDC_K4557     
Function   master regulator of natural competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 1582283..1592870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HK81_RS15215 (M636_15575) - 1582480..1583745 (-) 1266 WP_020903925.1 DUF945 family protein -
  HK81_RS15220 (M636_15580) - 1583932..1585872 (+) 1941 WP_025635282.1 ATP-binding protein -
  HK81_RS15225 (M636_15585) - 1585869..1586366 (+) 498 WP_020903927.1 response regulator -
  HK81_RS15230 (M636_15590) - 1586564..1587109 (+) 546 WP_005459590.1 hypothetical protein -
  HK81_RS15235 (M636_15595) tfoX 1587283..1587870 (-) 588 WP_005459593.1 TfoX/Sxy family DNA transformation protein Regulator
  HK81_RS15245 (M636_15605) - 1588241..1589161 (+) 921 WP_005483559.1 HDOD domain-containing protein -
  HK81_RS15250 (M636_15610) - 1589269..1590174 (+) 906 WP_005483516.1 lysine exporter LysO family protein -
  HK81_RS15255 (M636_15615) - 1590382..1590894 (+) 513 WP_005485575.1 hypothetical protein -
  HK81_RS15260 (M636_15620) panP 1591055..1592701 (+) 1647 WP_005485571.1 pyridoxal-dependent aspartate 1-decarboxylase PanP -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22459.81 Da        Isoelectric Point: 7.0628

>NTDB_id=60571 HK81_RS15235 WP_005459593.1 1587283..1587870(-) (tfoX) [Vibrio parahaemolyticus O1:K33 str. CDC_K4557]
MDMTDQAFFKYVRNFNEYQKRSMFGGIGLFSDDAMFALVSNDCCYLRGGNGLDEEFTLLNCEKYKHVKKQTTATVNYYDV
TDLFESGFTGLDDLLRKSIDCSIKERKYQKSSASKRLRDLPNMQLTLERMVKKAGIDDVETFLELGPVEVFNKVRVAYGN
DVDVKLLWKFAGAIDGVHWKLIQEPRKKQLLALCE

Nucleotide


Download         Length: 588 bp        

>NTDB_id=60571 HK81_RS15235 WP_005459593.1 1587283..1587870(-) (tfoX) [Vibrio parahaemolyticus O1:K33 str. CDC_K4557]
ATGGACATGACAGACCAAGCTTTTTTTAAATATGTACGCAATTTTAATGAGTATCAGAAACGTTCTATGTTTGGTGGTAT
CGGCTTGTTTAGCGATGACGCCATGTTTGCGCTTGTCAGCAATGATTGCTGTTATTTGCGCGGCGGTAATGGTTTAGACG
AAGAATTTACTCTGCTTAATTGTGAAAAATACAAGCACGTCAAAAAACAGACGACGGCTACTGTAAACTATTATGACGTA
ACCGATTTATTTGAGTCCGGATTTACTGGCCTTGACGATTTGTTACGAAAATCTATTGATTGCTCAATTAAGGAGCGAAA
ATACCAAAAGTCTTCTGCAAGTAAACGTTTGAGAGATCTACCGAACATGCAGCTTACATTAGAGCGCATGGTTAAAAAGG
CGGGTATTGATGATGTTGAAACCTTTTTGGAACTTGGTCCAGTTGAAGTGTTCAACAAAGTAAGAGTTGCTTACGGCAAT
GATGTTGACGTTAAACTGCTGTGGAAGTTTGCTGGTGCCATTGATGGTGTGCACTGGAAACTAATCCAAGAGCCGCGCAA
AAAACAGTTACTGGCACTGTGTGAATAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(11-101)

TfoX C-terminal domain (TfoX_C)

(114-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q87QA8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  tfoX Vibrio parahaemolyticus RIMD 2210633

100

100

1
  tfoX Vibrio campbellii strain DS40M4

91.795

100

0.918
  tfoX Vibrio cholerae O1 biovar El Tor str. N16961

68.394

98.974

0.677
  tfoX Vibrio cholerae O1 biovar El Tor strain DRC-193A

68.394

98.974

0.677
  tfoX Vibrio cholerae O1 biovar El Tor strain P27459

68.394

98.974

0.677
  tfoX Vibrio cholerae O1 biovar El Tor strain E7946

68.394

98.974

0.677
  tfoX Vibrio cholerae strain A1552

68.394

98.974

0.677
  tfoX Aliivibrio fischeri ES114

57.068

97.949

0.559

Multiple sequence alignment