Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NKZ80_RS00350 Genome accession   NZ_CP100330
Coordinates   57848..58747 (+) Length   299 a.a.
NCBI ID   WP_012774888.1    Uniprot ID   -
Organism   Streptococcus suis strain STC85     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 52848..63747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ80_RS00320 (NKZ80_00320) - 53102..53680 (+) 579 WP_023369011.1 CPBP family intramembrane glutamic endopeptidase -
  NKZ80_RS00325 (NKZ80_00325) - 53695..54123 (+) 429 WP_023369013.1 Msa family membrane protein -
  NKZ80_RS00330 (NKZ80_00330) - 54116..54880 (+) 765 Protein_45 ABC transporter ATP-binding protein -
  NKZ80_RS00335 (NKZ80_00335) ruvB 55217..56218 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  NKZ80_RS00340 (NKZ80_00340) - 56218..56964 (+) 747 WP_011921670.1 GNAT family N-acetyltransferase -
  NKZ80_RS00345 (NKZ80_00345) - 56966..57601 (+) 636 WP_023369015.1 HAD-IA family hydrolase -
  NKZ80_RS00350 (NKZ80_00350) comR 57848..58747 (+) 900 WP_012774888.1 helix-turn-helix domain-containing protein Regulator
  NKZ80_RS00355 (NKZ80_00355) - 59383..60321 (-) 939 WP_024402114.1 IS4 family transposase -
  NKZ80_RS00360 (NKZ80_00360) - 60458..61672 (+) 1215 WP_029749649.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  NKZ80_RS00365 (NKZ80_00365) - 61869..63392 (+) 1524 WP_044763875.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35405.30 Da        Isoelectric Point: 4.6492

>NTDB_id=604175 NKZ80_RS00350 WP_012774888.1 57848..58747(+) (comR) [Streptococcus suis strain STC85]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=604175 NKZ80_RS00350 WP_012774888.1 57848..58747(+) (comR) [Streptococcus suis strain STC85]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAATTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGCG
TAAATATATTAGGAAGCAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

100

100

1
  comR Streptococcus suis 05ZYH33

100

100

1
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371