Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   K8227_RS00330 Genome accession   NZ_CP082948
Coordinates   55402..56301 (+) Length   299 a.a.
NCBI ID   WP_012774888.1    Uniprot ID   A0A116VRL0
Organism   Streptococcus suis strain SZ1908     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50402..61301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8227_RS00305 (K8227_00305) - 50489..52201 (+) 1713 WP_012774887.1 ABC transporter ATP-binding protein -
  K8227_RS00310 (K8227_00310) - 52303..52476 (+) 174 WP_011921669.1 hypothetical protein -
  K8227_RS00315 (K8227_00315) ruvB 52771..53772 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  K8227_RS00320 (K8227_00320) - 53772..54518 (+) 747 WP_011921670.1 GNAT family N-acetyltransferase -
  K8227_RS00325 (K8227_00325) - 54520..55155 (+) 636 WP_011921671.1 HAD-IA family hydrolase -
  K8227_RS00330 (K8227_00330) comR 55402..56301 (+) 900 WP_012774888.1 helix-turn-helix domain-containing protein Regulator
  K8227_RS00335 (K8227_00335) - 56706..57869 (+) 1164 WP_011921673.1 IS110 family transposase -
  K8227_RS00340 (K8227_00340) - 58407..59345 (-) 939 WP_011921674.1 IS4 family transposase -
  K8227_RS00345 (K8227_00345) - 59485..60705 (+) 1221 WP_012774890.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35405.30 Da        Isoelectric Point: 4.6492

>NTDB_id=603808 K8227_RS00330 WP_012774888.1 55402..56301(+) (comR) [Streptococcus suis strain SZ1908]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=603808 K8227_RS00330 WP_012774888.1 55402..56301(+) (comR) [Streptococcus suis strain SZ1908]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116VRL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

100

100

1
  comR Streptococcus suis 05ZYH33

100

100

1
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371