Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   K8B76_RS08115 Genome accession   NZ_CP082820
Coordinates   1645258..1645917 (+) Length   219 a.a.
NCBI ID   WP_000565023.1    Uniprot ID   A0A0I8D2P0
Organism   Streptococcus pneumoniae strain SCAID PHRX1-2021     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1640258..1650917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B76_RS08090 (K8B76_08090) - 1640563..1640880 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  K8B76_RS08095 (K8B76_08095) - 1640895..1641791 (-) 897 WP_000825669.1 PEP phosphonomutase -
  K8B76_RS08100 (K8B76_08100) - 1641794..1643056 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  K8B76_RS08105 (K8B76_08105) - 1643336..1644514 (+) 1179 WP_000175880.1 ROK family transcriptional regulator -
  K8B76_RS08110 (K8B76_08110) - 1644742..1645188 (-) 447 WP_000155406.1 GNAT family N-acetyltransferase -
  K8B76_RS08115 (K8B76_08115) cclA/cilC 1645258..1645917 (+) 660 WP_000565023.1 A24 family peptidase Machinery gene
  K8B76_RS08120 (K8B76_08120) trpA 1645889..1646665 (-) 777 WP_001127007.1 tryptophan synthase subunit alpha -
  K8B76_RS08125 (K8B76_08125) trpB 1646658..1647881 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  K8B76_RS08130 (K8B76_08130) - 1647859..1648458 (-) 600 WP_000169872.1 phosphoribosylanthranilate isomerase -
  K8B76_RS08135 (K8B76_08135) trpC 1648445..1649212 (-) 768 WP_000076544.1 indole-3-glycerol phosphate synthase TrpC -
  K8B76_RS08140 (K8B76_08140) trpD 1649209..1650213 (-) 1005 WP_000658685.1 anthranilate phosphoribosyltransferase -
  K8B76_RS08145 (K8B76_08145) - 1650224..1650790 (-) 567 WP_000601921.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24921.13 Da        Isoelectric Point: 8.2409

>NTDB_id=602551 K8B76_RS08115 WP_000565023.1 1645258..1645917(+) (cclA/cilC) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=602551 K8B76_RS08115 WP_000565023.1 1645258..1645917(+) (cclA/cilC) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTAGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I8D2P0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

86.301

100

0.863