Detailed information NTG0602538

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: K8B76_RS05840
• Genome accession: NZ_CP082820
• Coordinates: 1193638..1194591 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain SCAID PHRX1-2021
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1188638..1199591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8B76_RS05815 (K8B76_05815)	-	1189129..1189221 (-)	93	Protein_1163	IS630 family transposase	-
K8B76_RS05820 (K8B76_05820)	-	1189635..1189976 (+)	342	Protein_1164	transposase	-
K8B76_RS05825 (K8B76_05825)	prsA	1190094..1191035 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
K8B76_RS05830 (K8B76_05830)	-	1191102..1191815 (-)	714	WP_001812425.1	O-methyltransferase	-
K8B76_RS05835 (K8B76_05835)	pepF	1191817..1193619 (-)	1803	WP_000244132.1	oligoendopeptidase F	Regulator
K8B76_RS05840 (K8B76_05840)	coiA	1193638..1194591 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
K8B76_RS05845 (K8B76_05845)	tehB	1194664..1195524 (-)	861	WP_000413758.1	SAM-dependent methyltransferase TehB	-
K8B76_RS05850 (K8B76_05850)	smpB	1195540..1196007 (-)	468	WP_001051753.1	SsrA-binding protein SmpB	-
K8B76_RS05855 (K8B76_05855)	rnr	1195970..1198324 (-)	2355	WP_000654901.1	ribonuclease R	-
K8B76_RS05860 (K8B76_05860)	secG	1198426..1198659 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
K8B76_RS05865 (K8B76_05865)	rpmG	1198699..1198848 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=602538 K8B76_RS05840 WP_000495909.1 1193638..1194591(-) (coiA) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=602538 K8B76_RS05840 WP_000495909.1 1193638..1194591(-) (coiA) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435