Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   K6973_RS02260 Genome accession   NZ_CP082206
Coordinates   420761..421447 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae strain DY107     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 415761..426447
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6973_RS02235 (K6973_02235) ktrB 415869..417245 (-) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -
  K6973_RS02240 (K6973_02240) rsmG 417329..418042 (-) 714 WP_138124835.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  K6973_RS02245 (K6973_02245) - 418195..418752 (+) 558 WP_138124837.1 LemA family protein -
  K6973_RS02250 (K6973_02250) htpX 418797..419690 (+) 894 WP_138124839.1 zinc metalloprotease HtpX -
  K6973_RS02255 (K6973_02255) - 419957..420490 (+) 534 WP_218655099.1 YceD family protein -
  K6973_RS02260 (K6973_02260) covR 420761..421447 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  K6973_RS02265 (K6973_02265) - 421453..422952 (+) 1500 WP_138124841.1 HAMP domain-containing histidine kinase -
  K6973_RS02270 (K6973_02270) nrdR 423159..423653 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  K6973_RS02275 (K6973_02275) - 423637..424815 (+) 1179 WP_218655100.1 DnaD domain protein -
  K6973_RS02280 (K6973_02280) dnaI 424816..425718 (+) 903 WP_218655101.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=600090 K6973_RS02260 WP_003049736.1 420761..421447(+) (covR) [Streptococcus dysgalactiae strain DY107]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=600090 K6973_RS02260 WP_003049736.1 420761..421447(+) (covR) [Streptococcus dysgalactiae strain DY107]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAATAGAGGAGATGATGAAATCTCTTTAACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACCAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACTGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425