Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   K6969_RS06825 Genome accession   NZ_CP082205
Coordinates   1408871..1410250 (-) Length   459 a.a.
NCBI ID   WP_029943182.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1403871..1415250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS06800 (K6969_06700) - 1404115..1405392 (-) 1278 WP_171942489.1 pyrimidine-nucleoside phosphorylase -
  K6969_RS06805 (K6969_06705) - 1405389..1405979 (-) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  K6969_RS06810 (K6969_06710) coaA 1406088..1407008 (+) 921 WP_002935283.1 type I pantothenate kinase -
  K6969_RS06815 (K6969_06715) rpsT 1407067..1407315 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  K6969_RS06820 (K6969_06720) - 1407541..1408770 (-) 1230 WP_171942488.1 transglutaminase domain-containing protein -
  K6969_RS06825 (K6969_06725) ciaH 1408871..1410250 (-) 1380 WP_029943182.1 sensor histidine kinase Regulator
  K6969_RS06830 (K6969_06730) ciaR 1410243..1410914 (-) 672 WP_014637852.1 response regulator transcription factor Regulator
  K6969_RS06835 (K6969_06735) - 1411056..1411634 (-) 579 WP_321537342.1 hypothetical protein -
  K6969_RS06840 (K6969_06740) phoU 1411784..1412440 (-) 657 WP_002940865.1 phosphate signaling complex protein PhoU -
  K6969_RS06845 (K6969_06745) pstB 1412469..1413227 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  K6969_RS06850 (K6969_06750) pstB 1413239..1414042 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  K6969_RS06855 (K6969_06755) pstA 1414067..1414954 (-) 888 WP_029177889.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51904.65 Da        Isoelectric Point: 6.8976

>NTDB_id=600053 K6969_RS06825 WP_029943182.1 1408871..1410250(-) (ciaH) [Streptococcus suis strain AKJ18]
MPKRLKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKNQKNTRDVEQLKLGINTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGGIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=600053 K6969_RS06825 WP_029943182.1 1408871..1410250(-) (ciaH) [Streptococcus suis strain AKJ18]
ATGCCTAAGCGATTAAAAAAATTAATGTACACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGTTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAGCCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCTAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGATGT
AGAACAGCTGAAATTAGGTATCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCAGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGGAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTTTCAG
CTTGGCTCATTTCTATCTTAGCCAGTATTTACCTATCGAATCTTAGTATGCGTCCAATTCTAATCAGTTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTTCGAAATATGCGATTATTGA
CAACGAACCTACTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATTGATGTTCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCTGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGACGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAACAAATTATCAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50

99.782

0.499
  ciaH Streptococcus pneumoniae D39

50

99.782

0.499
  ciaH Streptococcus pneumoniae R6

50

99.782

0.499
  ciaH Streptococcus pneumoniae TIGR4

50

99.782

0.499
  ciaH Streptococcus mutans UA159

49.89

99.129

0.495