Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   K6969_RS03750 Genome accession   NZ_CP082205
Coordinates   742526..743875 (+) Length   449 a.a.
NCBI ID   WP_024379730.1    Uniprot ID   A0A0Z8J8V5
Organism   Streptococcus suis strain AKJ18     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 737526..748875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS03720 (K6969_03660) - 738233..738514 (-) 282 WP_105096634.1 acyltransferase family protein -
  K6969_RS03725 (K6969_03665) - 738637..739296 (-) 660 WP_029174360.1 amino acid ABC transporter permease -
  K6969_RS03730 (K6969_03670) - 739311..740009 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  K6969_RS03735 (K6969_03675) - 740024..740863 (-) 840 WP_029174361.1 transporter substrate-binding domain-containing protein -
  K6969_RS03740 (K6969_03680) - 740874..741635 (-) 762 WP_171942725.1 amino acid ABC transporter ATP-binding protein -
  K6969_RS03745 (K6969_03685) micA 741829..742533 (+) 705 WP_004298854.1 response regulator YycF Regulator
  K6969_RS03750 (K6969_03690) micB 742526..743875 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  K6969_RS03755 (K6969_03695) vicX 743882..744685 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  K6969_RS03760 (K6969_03700) vga(F) 745047..746432 (+) 1386 WP_253911801.1 ABC-F type ribosomal protection protein Vga(F) -
  K6969_RS03765 (K6969_03705) pbp2b 746524..748596 (+) 2073 WP_171942726.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51035.09 Da        Isoelectric Point: 4.5202

>NTDB_id=600043 K6969_RS03750 WP_024379730.1 742526..743875(+) (micB) [Streptococcus suis strain AKJ18]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=600043 K6969_RS03750 WP_024379730.1 742526..743875(+) (micB) [Streptococcus suis strain AKJ18]
ATGATTAATCAATTACGTTATTTAATGACCACAGCAGAATTTTGGTTTGTTGTCATTTTGATTGGTTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCCCTCAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGATTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGTTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTAAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8J8V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635