Detailed information NTG0599992

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: K6974_RS08550
• Genome accession: NZ_CP082204
• Coordinates: 1694842..1695552 (-)
• Length: 236 a.a.
• NCBI ID: WP_024399189.1
• Uniprot ID: -
• Organism: Streptococcus suis strain FJSM5
• Function: repress the expression of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1695731..1696072	1694842..1695552	flank	179

Gene organization within MGE regions

Location: 1694842..1696072

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6974_RS08550 (K6974_08465)	covR	1694842..1695552 (-)	711	WP_024399189.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27173.64 Da
• Isoelectric Point: 6.7463

>NTDB_id=599992 K6974_RS08550 WP_024399189.1 1694842..1695552(-) (covR) [Streptococcus suis strain FJSM5]
MKSILIIEDEKDLSRILKMELEFEGYRVTVKENGRAGLMEALENTYDIILLDLMLPEMDGLEVTRRLRLVKQTVHIIIMT
AKDSVMDIVSGLDRGADDYLTKPFAIEELLARMRVFFRKQEIEQARITNQQSVTQQVVPEKGNVLNIIIDKASKSATYEG
HVVQMSSKELDLLAYLLEHQNEIVTRADIMANVWAGKKERQGSNIVDVYIRYLRRKLDRSLIRTIRGVGYIFGKEV

Nucleotide

• Length: 711 bp

>NTDB_id=599992 K6974_RS08550 WP_024399189.1 1694842..1695552(-) (covR) [Streptococcus suis strain FJSM5]
ATGAAAAGTATATTAATTATTGAAGATGAGAAAGATTTATCCAGAATATTAAAGATGGAGCTGGAGTTTGAAGGTTACCG
TGTGACTGTGAAAGAAAATGGTCGCGCTGGTCTTATGGAGGCTTTGGAAAATACTTATGACATTATTTTGTTAGATTTAA
TGTTACCTGAAATGGATGGGTTAGAAGTTACAAGACGATTGCGCTTGGTTAAACAAACTGTTCATATTATAATCATGACA
GCAAAAGATTCGGTAATGGATATTGTATCAGGGTTGGATCGTGGTGCAGACGACTATCTTACGAAACCATTTGCAATAGA
AGAGTTGCTTGCACGAATGAGAGTTTTTTTCAGAAAACAAGAAATTGAACAGGCTAGAATTACCAATCAACAGTCTGTAA
CACAGCAAGTAGTACCCGAAAAAGGCAATGTTTTAAATATCATCATAGATAAAGCCTCTAAATCTGCTACTTACGAAGGT
CATGTGGTGCAAATGTCCTCAAAAGAACTAGATCTATTGGCTTACCTTCTTGAGCATCAAAATGAAATTGTTACACGTGC
GGATATCATGGCCAATGTCTGGGCTGGGAAGAAAGAAAGACAAGGGTCTAATATAGTAGATGTCTACATCCGCTATTTAA
GAAGAAAATTAGATCGCTCACTCATTAGAACGATTCGTGGTGTCGGATACATTTTTGGGAAAGAAGTGTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (161-232)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	50.427	99.153	0.5
covR	Streptococcus salivarius strain HSISS4	48.718	99.153	0.483
vicR	Streptococcus mutans UA159	40.678	100	0.407
micA	Streptococcus pneumoniae Cp1015	38.723	99.576	0.386